ISBN: 0-470-84394-2

TOC:

SECTION I: AN INTRODUCTION TO BIOINFORMATICS FOR THE GENETICIST.
• Introduction: The Role of Genetic Bioinformatics (Michael R. Barnes and Ian C. Gray).
• Internet Resources for the Geneticist (Michael R. Barnes and Christopher Southan).
• Human Genetic Variation Databases and Concepts (Michael R. Barnes).
• Finding, Delineating and Analysing Genes (Christopher Southan).

  SECTION II: THE IMPACT OF COMPLETE GENOME SEQUENCES ON GENETICS.

• Assembling a View of the Human Genome (Colin A. Semple).
• Mouse and Rat Genome Informatics (Judith A. Blake, Janan Eppig and Carol J. Bult).
• Genetic and Physical Map Resources - An Integrated View (Michael R. Barnes).

  SECTION III: BIOINFORMATICS FOR GENETIC STUDY DESIGN.

• From Linkage Peak to Culprit Gene: Following Up Linkage Analysis of Complex Phenotypes with Population-based Association Studies (Ian C. Gray).
• Genetic Studies from Genomic Sequence (Michael R. Barnes).
• SNP Discovery and PCR-based Assay Design: From In Silico Data to the Laboratory Experiment (Ellen Vieux, Gabor Marth and Pui Kwok).
• Tools for Statistical Analysis of Genetic Data (Aruna Bansal, Peter R. Boyd and Ralph McGinnis).

  SECTION IV: BIOLOGICAL SEQUENCE ANALYSIS AND CHARACTERIZATION.

• Predictive Functional Analysis of Polymorphisms - An Overview (Michael R. Barnes).
• Functional In Silico Analysis of Non-Coding SNPs (Thomas Werner).
• Amino Acid Properties and Consequences of Substitutions (Matthew J. Betts and Robert B. Russell).

  SECTION V: GENETICS/GENOMICS INTERFACES.

• Gene Expression Informatics and Analysis (A. H. C. van Kampen, J. M. Ruijter, B. D. C. van Schaik, H. N. Caron and R. Versteeg).
• Proteomic Informatics (Jirtme Wojcik and Alexandre Hamburger).
• Concluding Remarks: Final Thoughts and Future Trends (Michael R. Barnes and Ian C. Gray).

Paperback, 350 Pages; April 2003; John Wiley