In Silico Technologies in Drug Target Identification and Validation


ISBN: 1574444786

 Author(s): Darryl Leon, Scott Markel (Eds)

TOC:

Target Identification

  • Pattern Matching
  • Tools for Computational Protein Annotation and Functional Assignment
  • The Impact of Genetic Variation on Drug Discovery and Development
  • Mining of Gene Expression Data

Target Validation

  • Text Mining
  • Pathways and Networks
  • Molecular Interactions: Learning from Protein Complexes
  • In Silico siRNA Design
  • Predicting Protein Subcellular Localization Using Intelligent Systems
  • Three-Dimensional Structures in Target Discovery and Validation

Recent Trends

  • Comparative Genomics
  • Pharmacogenomics
  • Target Identification and Validation Using Human Simulation Models
  • Using Protein Targets for In Silico Structure-Based Drug Discovery

Computational Infrastructure

  • Database Management
  • BioIT Hardware Configuration
  • BioIT Architecture: Software Architecture for Bioinformatics Research
  • Workflows and Data Pipelines
  • Ontologies

Index

Hardback, 504 pages, Publisher: CRC (June 13, 2006)
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