Speakers
 |
Confirmed Regional Keynote Speakers
- Maricel Kann (University of Maryland, USA)
- Christian Probst (Instituto Carlos Chagas-Fiocruz, Brazil)
- Francisco Melo Ledermann (Pontificia Universidad Católica de Chile, Chile)
- Emanuel Maltempi de Souza (Universidad Federal de Paraná, Brazil)
- Sandro Jose de Souza (Ludwig Institute for Cancer Research, Brazil)
- Fernán Aguero (Universidad Nacional de General San Martín, Argentina)
- Alejandro Colman-Lerner (Universidad de Buenos Aires-CONICET, Argentina)
Confirmed International Keynote Speakers
- Jane Loveland (Wellcome Trust Sanger Institute, UK)
- Daniel Hartl (Harvard University, USA)
- Winston Hide (Harvard School of Public Health, USA)
- Michal Linial (The Hebrew University of Jerusalem, Israel)
- Marc Marti-Renom (Príncipe Felipe Research Center, Spain)
- Eduardo Rocha (Université Pierre et Marie Curie-Paris 6; and Institut Pasteur, France)
- David S. Roos (University of Pennsylvania, USA)
- Burkhard Rost (Columbia University, USA)
- Terry Speed (Walter and Eliza Hall Institute of Medical Research, Australia; and University of California Berkeley, USA)
Schedule
Saturday, March 13, 2010
| 8:30 AM - 9:00 AM | Welcome remarks | |
| 9:00 AM - 10:00 AM | Opening Keynote: Burkhard Rost | Evolution teaches protein prediction |
Session I: New Sequencing Technologies: Applications and Impact
Discussion Leader: Christian Probst, Instituto Carlos Chagas - Fiocruz, Curitiba, Brazil
| 10:00 AM - 10:45 AM | International Keynote: Terry Speed | Analysis of ChIP-Seq data |
| 10:45 AM - 11:30 AM | Regional Keynote: Christian Probst | Omics approaches for the study of Chagas Disease |
| 11:30 AM - 12:00 PM | coffee break |
| 12:00 PM - 12:15 PM | Daniela Pavoni | Deep sequencing of Trypanosoma cruzi life cycle transcriptome |
| 12:15 PM - 12:30 PM | Victor Jin | A bin-based enrichment level threshold (BELT) algorithm to analyze ChIP-seq data |
| 12:30 PM - 12:45 PM | Michael Sammeth | Simulation of Digital Northerns and RNA-Seq Samba |
| 12:45 PM - 1:15 PM | Michael Tartakovsky | A centralized and scalable infrastructure approach to support next-generation sequencing at the National Institute of Allergy and Infectious Diseases |
| 1:15 PM - 2:45 PM | Lunch Break |
Session II: Protein Structure and Function
Discussion Leader: Francisco Melo Ledermann, Pontificia Universidad Católica de Chile, Santiago, Chile
| 2:45 PM - 3:30 PM | International Keynote: Marc Marti-Renom | Comparative docking for predicting molecular targets of known drugs |
| 3:30 PM - 4:15 PM | Regional Keynote: Francisco Melo Ledermann | Knowledge-based potentials for the characterization and prediction of protein binding sites |
| 4:15 PM - 4:45 PM | coffee break | |
| 4:45 PM - 5:00 PM | Alex Slater | Structural comparison and classification of the catalytic domains in DNA polymerases |
| 5:00 PM - 5:15 PM | Jorge Fernandez | New insights in oligopeptidases inhibition: Molecular dynamics studies of substrate/inhibitor accommodation |
| 5:15 PM - 5:30 PM | Nicolás Palopoli | Quality assessment of protein structure models using evolutionary information |
| 5:30 PM - 5:45 PM | Cassiana Chassot Fülber | Reconstruction of MHC alleles by cross modeling and structural assessment |
| 5:45 PM - 6:00 PM | Daniel Almonacid | Classification of enzyme function according to similarities in reaction mechanisms and common substrate substructures |
| 9:00 AM - 9:45 AM | International Keynote: Jane Loveland | Providing a vertebrate reference geneset |
| 9:45 AM - 10:30 AM | Regional Keynote: Maricel Kann | Coevolution of interacting proteins: What is behind the mirror tree? |
| 10:30 AM - 11:00 AM | coffee break |
| 11:00 AM - 11:15 AM | Tiago Mendes | Comparative proteome analysis of protozoan parasites: tandem repeat proteins and epitope predictions |
| 11:15 AM - 11:30 AM | Andrzej Brodzik | A combinatorial-analytic approach to single nucleotide polymorphism detection |
| 11:30 AM - 11:45 AM | Agustina Olivera-Couto | Bioinformatic insight into eisosomes' molecular function |
| 11:45 AM - 1:30 PM | Lunch Break |
Session IV: Microbial Genomics and Metagenomics
Discussion Leader: Elena Fabiano, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay
| 1:30 PM - 2:15 PM | International Keynote: Eduardo Rocha | Uses for comparative (meta)genomics in evolutionary ecology |
| 2:15 PM - 3:00 PM | Regional Keynote: Emanuel de Souza | Discovery of new hydrolytic enzymes by metagenomics |
| 3:00 PM - 3:30 PM | coffee break |
| 3:30 PM - 3:45 PM | Alejandro Reyes | Metagenomic analysis of bacteriophage present in the gut microbiota of monozygotic twins and their mothers |
| 3:45 PM - 4:00 PM | Federico Rosconi | Iron uptake systems in the grass endophyte Herbaspirillum seropedicae Z67: structure and transport of an NRPS-siderophore |
| 4:00 PM - 4:15 PM | Maria Cecilia Rodríguez | Characterization and identification of hydrolytic enzymes of potential interest in biofuel production by using metagenomics approaches |
| 4:15 PM - 4:30 PM | Cecilia Callejas | 16S rRNA gene diversity in cyanobacterial-bacterial mat consortia of King George Island, Maritime Antarctica |
| 4:30 PM - 5:00 PM | Burkhard Rost | ISCB Open Meeting |
| 5:00 PM - 7:00 PM | Poster session even numbers |
Monday, March 15, 2010:
Session V: Bioinformatics of Health and Disease in Latin America
Session Va: Computational Biomedicine
Discussion Leader: Sandro Jose de Souza, Ludwig Institute for Cancer Research, Sao Paulo, Brazil
| 9:00 AM - 9:45 AM | International Keynote: Winston Hide | When peculiar gene expression makes the difference |
| 9:45 AM - 10:30 AM | Regional Keynote: Sandro de Souza | Deciphering the human surfaceome |
| 10:30 AM - 11:00 AM | coffee break |
| 11:00 AM - 11:15 AM | Esteban Czwan | Theme-driven cancer survival analysis |
| 11:15 AM - 11:30 AM | Ronnie Alves | Gene Association Analysis of Gene Expression Data |
| 11:30 AM - 11:45 AM | Ashwani Sharma | Finding putative drug against H1N1 Virus (Influenza A virus) by computational virtual screening approach |
| 11:45 AM - 12:00 PM | Tom Kelsey | The dynamics of human ovarian reserve |
| 12:00 PM - 12:15 PM | Veronika Stoka | The lysosomal apoptosis signaling pathway is a complex biological network |
| 12:15 PM - 12:30 PM | Juan Jose Cifuentes | Structural protein motifs that recognize damaged DNA |
| 12:30 PM - 2:00 PM | Lunch Break |
Session Vb: Infectious Diseases and Drug Target Discovery
Discussion Leader: Fernán Aguero, Universidad Nacional de General San Martín, Buenos Aires, Argentina
| 2:00 PM - 2:45 PM | International Keynote: David S. Roos | Designing & Mining (Pathogen) Genome Databases: From Genes to Drugs & Vaccines |
| 2:45 PM - 3:30 PM | Regional Keynote: Fernán Aguero | The TDR Targets Database: identification and prioritization of drug targets for neglected diseases |
| 3:30 PM - 4:00 PM | coffee break | |
| 4:00 PM - 4:15 PM | Axel Soto | A new method for multi-objective selection of molecular descriptors for QSAR/QSPR |
| 4:15 PM - 4:30 PM | Adhemar Zerlotini | Integration and use of Schistosoma mansoni genomic data towards the identification of candidate therapeutic targets |
| 4:30 PM - 4:45 PM | Guido Nuñez-Mujica | The role of biosynthetic pathways as regulation mechanism of glycolysis in Trypanosoma brucei |
| 4:45 PM - 5:00 PM | Benjamin Woodcroft | An Integrative Bioinformatic Predictor of Protein Sub-Cellular Localisation in Malaria |
| 5:00 PM - 7:00 PM | Poster session odd numbers |
| 8:30 PM | Conference Banquet |
Tuesday, March 16, 2010
Session VI: Functional Genomics and Systems Biology
Discussion Leaders: Wim Degrave, Instituto Oswaldo Cruz - Fiocruz, Rio de Janeiro, Brazil and Alejandro Colman-Lerner, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina
| 9:00 AM - 9:45 AM | International Keynote: Michal Linial | Navigating the twilight zone: Exploring overlooked functions among cell modulators |
| 9:45 AM - 10:30 AM | Regional Keynote: Alejandro Colman-Lerner | Signal anticipation in a GPCR pathway: single cell measurements of scaffold recruitment show rapid dose response alignment before receptor binding reaches equilibrium |
| 10:30 AM - 11:00 AM | coffee break |
| 11:00 AM - 11:15 AM | Christophe Lefèvre | Comparative genomics of lactation |
| 11:15 AM - 11:30 AM | Priscila Grynberg | Analysis of Trypanosoma cruzi gene expression in response to ionizing radiation using the DNA microarray technique |
| 11:30 AM - 11:45 AM | Lucía Durrieu | Quantitative study of mother-daughter asymmetry in Ace2 localization in yeast |
| 11:45 AM - 12:00 PM | Miguel Ponce de Leon | Calculating metabolic responses from the stoichiometric network and optimization principles |
| 12:00 PM - 12:15 PM | Dietlind Gerloff | Functional Genomic Data Visualisation for Biologist Users: Prototype Tools Enabling “Exploration-Style Analysis” of Malaria and Yeast Data |
| 12:15 PM - 1:15 PM | Closing Keynote: Daniel Hartl | Natural History of the Malaria Parasite and its Genome |
| 1:15 PM - 1:30 PM | Closing Remarks |
NOTE: Schedule subject to change.
Instructions for Authors
Oral presenters: All accepted talks have a total duration of 15 minutes. Please prepare a talk that is around 12 minutes long to leave 3 minutes for questions. To allow a quick and easy transition between speakers, a laptop computer will be at the podium, and all speakers should load their presentations in this computer during the coffee break preceding the session at which they will present. The computer will have the latest versions of PowerPoint and Adobe Reader software.
Poster presenters: There will be two poster sessions with a duration of 2 hours each. Authors of even numbered posters should be present by their posters on Sunday 14th March 5pm-7pm. Authors of odd numbered posters should be by their posters on Monday 15th March 5pm-7pm. See the Accepted Abstracts below to find out whether your poster has been assigned an even or an odd number). The poster boards at the exhibition park of the LATU will hold posters of up to 0.96m wide by 2.4m high (up to 37 inches wide by 94 inches high). Even numbered posters can be put up either on Satruday 14th or Sunday 15th, and should be taken down immediately following the poster session on Sunday 15th. Odd numbered posters have to be put up on Monday 16th, and should be removed by 1.30pm on Tuesday 17th.
Accepted Abstracts
|
New Sequencing Technologies: Applications and Impact |
|
|
1 |
Deep sequencing of Trypanosoma cruzi life cycle transcriptome Daniela Parada Pavoni, Christian Macagnan Probst, Rita de Cássia Pontello Rampazzo, Marco Aurélio Krieger. |
|
2 |
A bin-based enrichment level threshold (BELT) algorithm to analyze ChIP-seq data Xun Lan, Sankaran Kasiviswanathan, Jeff Apostolos, Brian A. Kennedy, Tim H.-M. Huang and Victor X. Jin |
|
3 |
16S rRNA hypervariable tag pyrosequencing for the study of microbial diversity in a protected coastal lagoon (Laguna de Rocha, Uruguay) Cecilia Alonso, Claudia Piccini |
|
4 |
Simulation of Digital Northerns and RNA-Seq Samba Michael Sammeth, Paolo Ribeca, Roderic Guigó |
|
5 |
mRNA decay profiles in Trypanosoma cruzi obtained by deep sequencing Eduardo Lemons Francisco, Daniela Parada Pavoni, Rita de Cássia Pontello Rampazzo, Marco Aurélio Krieger, Christian Macagnan Probst |
|
6 |
A centralized and scalable infrastructure approach to support next-generation sequencing at the National Institute of Allergy and Infectious Diseases Nick Weber, Vivek Gopalan, Mariam Quiñones, Hugo Hernandez, Robert Reed, Kim Kassing, Yentram Huyen, Michael Tartakovsky |
|
Protein Structure and Function |
|
|
7 |
A Study of Hydrophobic Effect on the Protein Folding Using Monte Carlo in 2D Lattice and Cubic lattice Luis Scott, Pierre Tisseur, Adriano Faria |
|
8 |
Using genetic algorithms and rotamer library to investigate protein-ligand docking Luis Scott, Angelica Lima, Eric Phillot |
|
9 |
Applying data mining to investigate the protein folding and extract rules of formation of secondary structure Luis Scott, Maria Barioni, Digo Estelle |
|
10 |
Modelling and Evaluation of the Tridimensional Structure of E5, an Oncoprotein from the Human Papillomavirus (HPV) Types 06 and 16 Nilson Nicolau Junior, Silvana Giuliatti |
|
11 |
In silico screening for Phospholipase A2 of Apis Mellifera with Fragment Library Daniel M. M. Jorge, Vinicius B. da Silva, Carlos H. T. P. Silva, Andreimar M. Soares, Silvana Giuliatti |
|
12 |
Homology relationship based on the amino acid properties Verónica Alvarez and Luis Diambra |
|
13 |
Structural comparison and classification of the catalytic domains in DNA polymerases Alex W. Slater and Francisco Melo |
|
14 |
New insights in oligopeptidases inhibition: molecular dynamics studies of substrate/inhibitor accommodation Jorge H. Fernandez |
|
15 |
A simple solution to undercome pitfalls of structural alignment methods in the classification of protein structures where high sequence divergence exists Javier Castellanos, Alex W. Slater and Francisco Melo F. |
|
16 |
PDIdb: a novel database containing the three-dimensional interfaces of protein-DNA complexes Tomas Norambuena and Francisco Melo |
|
17 |
Classification of enzyme function according to similarities in reaction mechanisms and common substrate substructures Daniel E. Almonacid, Patricia C. Babbitt |
|
18 |
Reconstruction of MHC alleles by cross modeling and structural assessment Cassiana Fülber, Samuel Cibulski, Dinler Antunes, Maurício Rigo, José Chies, Marialva Sinigaglia, Gustavo Vieira |
|
19 |
A new approach to fast calculation of Atomic Contact Energy for protein-protein interaction prediction Cristian Sebastian Rocha, Luis Gómez Déniz |
|
20 |
A simplified 1-D representation of electrostatic surface properties of modeled protein structures enables screening for evolutionary adaptive protein sites Dietlind L. Gerloff, Shakir Ali, Marcos Woehrmann |
|
21 |
Distribution and extension of protein conformational diversity Ezequiel Iván Juritz, Nicolás Palopoli, Sebastián Fernández Alberti, Gustavo Parisi |
|
22 |
Quality assessment of protein structure models using evolutionary information Nicolas Palopoli, Ezequiel Juritz, Sebastián Fernandez Alberti, Diego Gomez Casati, Gustavo Parisi |
|
23 |
Structural and Biological Analysis of Retromer Complex in the protozoan parasite Giardia lamblia Silvana L Miras, María R Rivero, Andrea S Ropolo and María C Touz. |
|
24 |
Role of heme distortion on oxygen affinity in heme proteins: the protoglobin case Damián E. Bikiel, Flavio Forti, Leonardo Boechi, Marco Nardini, F. Javier Luque, Marcelo A. Martí, and Darío A. Estrin |
|
25 |
A new method combining mutual information and conservation improves the detection of catalytic sites in proteins Elin Teppa, Tomas Di Doménico, Morten Nielsen and Cristina Marino Buslje |
|
26 |
Comparison of structural, dynamical and protein carbohydrate interaction properties of human galectins Carlos M. A. Guardia, Diego F. Gauto, Santiago Di Lella, Gabriel A. Rabinovich, Marcelo A. Martí and Darío A. Estrin |
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Sequence Analysis, Comparative Genomics and Evolution |
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|
27 |
In silico testing of 23S rRNA primers for further use in cyanobacterial mats biodiversity studies Cristian Coman, Adriana Bica, Bogdan Druga, Ana Nicoara and Nicolae Dragos |
|
28 |
Protein Data Integration for Phylogenetic Data Mining Humberto Razente, Antonio Braz, Luis Scott |
|
29 |
Genomic Ecology: genes competing for a metabolic niche? Marcos Catanho, Ana Carolina Ramos Guimarães, Thomas Dan Otto, Fernando Alvarez-Valin, Wim Degrave & Antonio Basílio de Miranda |
|
30 |
A computational pipeline for diagnostic biomarker discovery in the human pathogen Trypanosoma cruzi Santiago Carmona, Paula Sartor, Susana Leguizamón, Oscar Campetella and Fernán Agüero |
|
31 |
Compositional Profile of the Human Genome at the Chromosome Level Victor Sabbia, Hector Romero, Hector Musto, Hugo Naya |
|
32 |
Analogous enzymes inside the Tritryps genomes Ana Carolina Ramos Guimarães, Wim Maurits Degrave, Antonio Basílio de Miranda |
|
33 |
Comparative microbial genomics in Pasteurellaceae family using second generation sequencing Isabelle da Piedade, Timothy J Johnson, Anders M Bojesen |
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34 |
The Genome Comparison Project and the Protein World Database Thomas Dan Otto, Marcos Catanho, Cristian Tristão, Márcia Bezerra, Renan Mathias Fernandes, Guilherme Steinberger Elias, Alexandre Capeletto Scaglia, Bill Bovermann, Viktors Berstis, Sergio Lifschitz, Antonio Basílio de Miranda & Wim Degrave |
|
35 |
Searching for signals in the Tritryps genomes Pablo Smircich, Gustavo Cerqueira, Najib El-Sayed, Beatriz Garat |
|
36 |
Comparative proteome analysis of protozoan parasites: tandem repeat proteins and epitope predictions Tiago Mendes, Frascisco Lobo, Leandro Freitas, Tiago Rodrigues, Daniella Bartholomeu |
|
37 |
Codon usage analysis in Enterobacteriaceae: towards the detection of ancestral optimal triplets Juan Baraibar, Andrés Iriarte, Héctor Romero, Héctor Musto |
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38 |
Selection to less thymine dimmers content in the DNA of resistant UV bacteria and archaea Jorge Bresciano |
|
39 |
Sequence analysis of class 1 integron’s integrase gene and the associated attI1 recombination site María Paula Quiroga, Maximiliano Nardelli, María Soledad Ramírez, Daniela Centrón |
|
40 |
Lifestyle, gene repertory and base composition bias in spirochetes Natalia Rego, Martín Graña, Guillermo Lamolle, Fernando Alvarez-Valin, Hugo Naya |
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41 |
An easy way to incorporate phylogenetic uncertainty in the comparative model Lucía Spangenberg, Natalia Rego, Hector Romero, Hugo Naya |
|
42 |
Integrated in silico-wet biology approach for improving the annotation of Babesia bigemina perforin family Romina Petrigh, Natalia Rego, Beatriz Valentini, Ignacio Echaide, Hugo Naya, Marisa Farber |
|
43 |
A Combinatorial-Analytic Approach to Indel and Single Nucleotide Polymorphism Detection Andrzej K. Brodzik |
|
44 |
Molecular Evolution and Functional Divergence of Alcohol Dehydrogenases in Animals, Fungi and Plants Thompson, C.E.; Freitas, L.B.; Salzano, F.M. |
|
45 |
Discovery of a new conserved tandem motif upstream of outer membrane hemin transporters in alpha and beta-proteobacteria Uriel Koziol, Vanesa Amarelle, Federico Rosconi, Francisco Noya, Mark R. O´Brian and Elena Fabiano |
|
46 |
Bioinformatic insight into eisosomes' molecular function Agustina Olivera-Couto and Pablo S. Aguilar |
|
47 |
Identifier (ID) elements inserted into non-coding regions of pol II-primary transcripts are not related to the regulation of tissue-specific gene expression in rat Andrés Goldman, Evangelina González-López, Carlos A. Capoano and Adriana Geisinger |
|
48 |
12D3 gene sequence conservation in Mexican isolates of Babesia bovis Jocelin Perez, Javier Pérez, Patricia Vargas, Antonio Alvarez, Carmen Rojas, Julio V. Figueroa |
|
49 |
Initial Babesia bigemina gene identification by Expressed Sequence Tags analysis of the intraerythrocytic stage Javier Perez, Patricia Vargas, Antonio Alvarez, Carmen Rojas, Julio V. Figueroa |
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Microbial Genomics and Metagenomics |
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|
50 |
A Hidden Markov Model that finds genes in Enterobacter DNA Hebert HSG Soto |
|
51 |
Metagenomic analysis of bacteriophage present in the gut microbiota of monozygotic twins and their mothers Alejandro Reyes, Matthew Haynes, Forest Rohwer and Jeffrey Gordon |
|
52 |
Iron uptake systems in the grass endophyte Herbaspirillum seropedicae Z67: structure and transport of an NRPS-siderophore Federico Rosconi, Fabio Pedrosa, Emanuel de Souza and Elena Fabiano |
|
53 |
Characterization and identification of hydrolytic enzymes of potential interest in biofuel production by using metagenomics approaches Cecilia Rodriguez, Daniela Senatore, Vanesa Amarelle, Adriana Peri, Uriel Koziol, Elena Fabiano, and Francisco Noya |
|
54 |
16S rRNA gene diversity in cyanobacterial-bacterial mat consortia of King George Island, Maritime Antarctica Cecilia Callejas, Emanuel M. de Souza, and Silvia Batista |
|
55 |
Tuning a phylogenetic classification for metagenomic samples based on homology, using simulated data Emiliano Pereira, Héctor Romero, Héctor Musto |
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Computational Biomedicine |
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|
56 |
Gene Association Analysis of Gene Expression Data Ronnie Alves, Domingo S. Rodriguez-Baena, Jesus S. Aguilar-Ruiz |
|
57 |
Finding putative drug against H1N1 Virus (Influenza A virus) by computational virtual screening approach. Ashwani Sharma, Ashish V. Tendulkar, Kuppili Raja Reddy, Pramod Wangikar |
|
58 |
The dynamics of human ovarian reserve T W Kelsey and W H B Wallace |
|
59 |
The lysosomal apoptosis signaling pathway is a complex biological network Veronika Stoka, Boris Turk, Vito Turk |
|
60 |
Theme-driven cancer survival analysis Esteban Czwan, Benedikt Brors, David Kipling |
|
61 |
Structural protein motifs that recognize damaged DNA Juan José Cifuentes and Francisco Melo |
|
62 |
In silico studies of sesquiterpene lactones with inhibitory activity of Nuclear Factor kappa B Luis Alejandro Castro, Sara Aguilera Morales, Federico Iribarne Restuccia, Margot Paulino Zunini |
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Infectious Diseases and Drug Target Discovery |
|
|
63 |
Methodological developments based on genetic algorithm and normal mode analysis for performing protein-ligand and protein-protein docking simulations Luis Scott, Perahia, David, Angelica Lima, Eric Phillot |
|
64 |
Studies on the interactions of the enzyme InhA from Mycobacterium tuberculosis with small drug-like molecules Ivani Pauli, Osmar Norberto de Souza, Luiz Augusto Basso, Diógenes Santiago Santos |
|
65 |
A based learning machine web system for selection medicinal plants of the cerrado with antimicrobial properties Saulo França Amui, Lucas Junqueira de Freitas Morel, Ana Maria Soares Pereira, Silvana Giuliatti |
|
66 |
Applying Model Trees on Flexible-Receptor Docking Experiments to select promising protein receptor snapshots Karina S. Machado, Ana T. Winck, Duncan D. A. Ruiz, Osmar Norberto de Souza |
|
67 |
Designing and implementing chemoinformatic approaches in TDR Targets Database: linking genes to chemical compounds in tropical disease causing pathogens María Paula Magariños, John Overington, Santiago Carmona, Dhanasekaran Shanmugam, Maria Doyle, Stuart Ralph, Greg Crowther, Christiane Hertz-Fowler, Solomon Nwaka, Matt Berriman, David Roos, Wes Van Voorhis, Fernán Agüero |
|
68 |
A Context-Based Preprocessing on Flexible-Receptor Docking Data Ana T. Winck, Karina S. Machado, Osmar Norberto de Souza, Duncan D. A. Ruiz |
|
69 |
A new method for multi-objective selection of molecular descriptors for QSAR/QSPR Axel J. Soto, Rocío L. Cecchini, Gustavo E. Vazquez, Ignacio Ponzoni |
|
70 |
Alpha-Mannosyltransferase (pimA) from Mycobacterium tuberculosis H37Rv: molecular modeling, virtual screening and molecular dynamic studies Luís Fernando Saraiva Macedo Timmers, Luiz Augusto Basso, Diógenes Santiago Santos and Walter Filgueira de Azevedo Jr. |
|
71 |
Integration and use of Schistosoma mansoni genomic data towards the identification of candidate therapeutic targets Adhemar Zerlotini, Mark Heiges, Haiming Wang, Regina Coeli, Romulo Moraes, Anderson Dominitini, Jessica Kissinger, Guilherme Oliveira |
|
72 |
A mapping method for linking chemical compounds to biological and physicochemical properties in drug discovery Axel J. Soto, Marc Strickert, Gustavo E. Vazquez |
|
73 |
The effect of InhA flexibility in docking simulations with ethionamide and triclosan Elisangela M. L. Cohen, Karina S. Machado, Osmar Norberto de Souza |
|
74 |
Peptide:MHC complexes reconstruction to infer binding affinity for the HLA-A*0201 allele Maurício Menegatti Rigo, Dinler Amaral Antunes, Samuel Paulo Cibulski, Cassiana Chassot Fülber, Marialva Sinigaglia, José Artur Bogo Chies, Gustavo Fioravanti Vieira |
|
75 |
The role of biosynthetic pathways as regulation mechanism of glycolysis in Trypanosoma brucei Guido D. Núñez-Mujica, Antonio Parravano, Juan Luis Concepción |
|
76 |
Prediction of B-cell epitopes of dengue virus non-structural 1 (NS1) protein involved in dengue serotype specificity Luiza A. Castro-Jorge, Benedito A. L. Fonseca |
|
77 |
An Integrative Bioinformatic Predictor of Protein Sub-Cellular Localisation in Malaria Woodcroft BJ, Scanlon K, Doyle MA, Bailey J, Speed TP, Ralph SA |
|
78 |
Identification of Novel Epitopes of the Ebola Virus Towards Rational Vaccine Design, Virus Evolution, and Protein Conservation. Sophia Banton, Zvi Roth, Mirjana Pavlovic |
|
79 |
A Study of Molecular Descriptor to Rank Candidate Ligands to Inhibit the InhA Receptor Christian V. Quevedo, Ana T. Winck, Karina S. Machado, Osmar Norberto de Souza, Duncan D. A. Ruiz |
|
80 |
Computational prediction of putative inhibitor against Thymidine kinase enzyme of Herpes simplex virus (HSV-1): An approach for Drug discovery Ashwani Sharma, Ashish V. Tendulkar, Pramod Wangikar |
|
Functional Genomics and Systems Biology |
|
|
81 |
Phenotypic Effects of Network Rewiring in Regulatory Hierarchies Nitin Bhardwaj, Philip M. Kim and Mark B. Gerstein |
|
82 |
wAtPIN: Weighted Arabidopsis thaliana Protein Interaction Network Marcelo M. Brandão, Luiza L. B. Dantas, Marcio C. Silva-Filho |
|
83 |
Developmental aging in mammals: a systems biology analysis of epigenetic, development and senescence mechanisms Bruno César Feltes, Joice de Faria Poloni, Diego Bonatto |
|
84 |
Comparative genomics of lactation Christophe Lefèvre, Karenza Menzies, Julie sharp, Kevin Nicholas |
|
85 |
Modeling gene expression: noise and cooperativity Pablo S. Gutierrez, Laura Calcagni, Diana Monteoliva and Luis Diambra |
|
86 |
Analysis of Trypanosoma cruzi gene expression in response to ionizing radiation using the DNA microarray technique Priscila Grynberg, Danielle G. Passos-Silva, Roberto Hirata Jr., Andrea M. Macedo, Eduardo J. Neves, Carlos R. Machado, Daniella C. Bartholomeu, Glória R. Franco |
|
87 |
Differentially Expressed Genes in Microarray Analysis of Rheumatoid Arthritis Disease Luiz Fernando M. Pignata, Nilson Nicolau Júnior, Flávia Sacilotto Donaires, Cristina M. Junta, Geraldo A. Passos, Silvana Giuliatti |
|
88 |
A systems biology view about the role of nuclear melatonin receptors in neurogenesis Joice de Faria Poloni, Bruno César Feltes, Diego Bonatto |
|
89 |
Towards a taxonomy of centrality measures for gene expression data sets Nicolás Pozo-Rojas, Mario Inostroza-Ponta, Pablo Moscato |
|
90 |
Dose response alignment in a G protein coupled receptor pathway Alan Bush, Ariel Chernomoretz, Rodrigo Laje, Alejandro Colman-Lerner |
|
91 |
Gene Ontology guided clustering of gene expression profiles Ariel Chernomoretz |
|
92 |
Quantitative study of mother-daughter asymmetry in Ace2 localization in yeast Lucía Durrieu, Gunnar Cedersund, Alan Bush y Alejandro Colman-Lerner |
|
93 |
RNA-binding proteins interactome in Trypanosoma cruzi. Henrique Preti, Alessandro Afornali, Newton de Medeiros Vidal, Christian Macagnan Probst, Marco Aurélio Krieger |
|
94 |
Detecting Circadian Genes from Microarray Carla Layana and Luis Diambra |
|
95 |
Animated visualization of biological processes Tatiana Cartagena de Oliveira, Marcelo Cezar Pinto |
|
96 |
Computational analysis of the Schistosoma mansoni genome for the identification of vaccine candidates Rômulo Moraes, Jerônimo Ruiz, Adhemar Zerlotini, Guilherme Oliveira |
|
97 |
Sunflower Functional Genome Database, a curated unigene database to support functional diversity studies in sunflower Fernandez, P., Blesa, D., Príncipi, D., Fusari, C., Soria, M., Reynares, C., Angelone, L., Delfino, S., Conesa, A., Dopazo, J., Tapia, E., Heinz, R.A. and Paniego, N. |
|
98 |
Cell-fate decisions in mating pheromone stimulated yeast. A systems biology study. Ariel Chernomoretz, Luciana Bruno, Pablo Balenzuela, Rodrigo Laje, Rodrigo Baltanás, Elizabeth Kennedy, Alejandro Colman-Lerner |
|
99 |
Calculating metabolic responses from the stoichiometric network and optimization principles Miguel Ponce de Leon, Hector Cancela, Luis Acerenza |
|
100 |
KinetoUTR: a tool for visualization and analyses of mRNA regulatory elements in kinetoplatids Newton de Medeiros Vidal, Marco Aurélio Krieger, Christian Macagnan Probst |
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101 |
Understanding implications of tissue-specific codon usage in human Tamara Fernández, Lucía Spangenberg, Ariel Chaparro, Natalia Rego, Mónica Marín, Hugo Naya |
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102 |
SPARC gene, identified in a multi-organism functional genomics approach, impairs wound healing in Drosophila melanogaster Federico Prada, A. Chernomoretz, C. Alvarez-Fernandez, A. Llera, P. Wappner, E. Martín Blanco, O. Podhajcer |
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103 |
Functional Genomic Data Visualisation for Biologist Users: Prototype Tools Enabling "Exploration-Style Analysis" of Malaria and Yeast Data Dietlind L. Gerloff, Joanna Sharman, Richard Orton |
