BRIDGE - Building a Bioinformatics Ressource for the Integration of heterogeneous Data from Genomic Explorations into a platform for Systems Biology
Alexander Goesmann1, Folker Meyer2, D. Bartels, L. Krause, B. Linke, O. Rupp, A. Pühler
1Alexander.Goesmann@Genetik.Uni-Bielefeld.DE, Center for Genome Research, Bielefeld University; 2fm@Genetik.Uni-Bielefeld.DE, Center for Genome Research, Bielefeld University
The flood of data acquired from the increasing number of
publicly available prokaryote genomes has led to new demands for bioinformatics
software. With the growing amount of information resulting from high
throughput experiments new questions arise that often focus on the
comparison of genes, genomes and their expression profiles. Inferring
new knowledge by combining different kinds of post genomics data
obviously necessitates the development of new approaches that allow
the integration of variable data sources into a flexible framework.
We describe our concept for the integration of
heterogeneous data into a platform for systems biology. We have
implemented a Bioinformatics
Resource for the Integration of heterogeneous Data from Genomic Explorations (BRIDGE) and illustrate
the usability of our approach as a platform for systems biology for
two sample applications.