TOC:
Preface (J. Wooley).
Introductory Comments
(The Editors).
SECTION I: INTRODUCTION.
- What is Bioinformatics
and Structural Bioinformatics (R. Altman & J. Dugan).
- Fundamentals of
Protein Structure (E. Scheeff & L. Fink).
- Fundamentals of
DNA and RNA Structure (S. Neidle, et al.).
- Computational
Aspects of High-Throughput Crystallographic Macromolecular Structure
Determination (P. Adams, et al.).
- Macromolecular
Structure Determination by NMR Spectroscopy (J. Markley, et al.).
- Electron Microscopy
(N. Volkmann & D. Hanein).
- Molecular Visualization
(J. Tate).
SECTION II: DATA
REPRESENTATION AND DATABASES.
- The PDB Format,
mmCIF Formats and Other Data Formats (J. Westbrook & P. Fitzgerald).
- The Protein Data
Bank (The PDB Team).
- The Nucleic Acid
Database (H. Berman, et al.).
- Other Structure
Based Databases (H. Weissig & P. Bourne).
SECTION III: COMPARATIVE
FEATURES.
- Protein Structure
Evolution and the SCOP Database (B. Reddy & P. Bourne).
- The CATH Domain
Structure Database (C. Orengo, et al.).
- Structural Quality
Assurance (R. Laskowski).
- All-Atom Contacts:
A New Approach to Structure Validation (J. Richardson).
- Structure-Structure
Comparison and Alignment (I. Shinadyalov & P. Bourne).
SECTION IV: STRUCTURE
AND FUNCTIONAL ASSIGNMENT.
- Secondary Structure
Assignment (C. Andersen & B. Rost).
- Identifying Structural
Domains in Proteins (L. Wernisch & S. Wodak).
- Inferring Protein
Function from Structure (G. Bartlett, et al.).
SECTION V: PROTEIN
INTERACTIONS.
- Prediction of
Protein-Protein Interactions from Evolutionary Information (A. Valencia
& F. Pazos).
- Electrostatic
Interactions (N. Baker & J. McCammon).
SECTION VI: PROTEINS
AS DRUG TARGETS.
- Principles and
Methods of Docking and Ligand Design (J. Krumrine, et al.).
- Structural Bioinformatics
in Drug Discovery (E. Fauman, et al.).
SECTION VII: STRUCTURE
PREDICTION.
- The CASP Experiment
and Its Findings (TBN).
- Homology Modeling
(E. Krieger, et al.).
- Fold Recognition
Methods (A. Godzik).
- Ab Initio
Methods (D. Chivian, et al.).
- Prediction in
1D: Secondary Structure, Membrane Helices, and Accessibility (B. Rost).
SECTION VIII:
THE FUTURE.
- Structural Genomics
(S. Burley & J. Bonanno).
- Epilogue.
Hardcover, 649 Pages;
February 2003; John Wiley |