The
massive research effort known as the Human Genome Project is an attempt
to record the sequence of the three trillion nucleotides that make up
the human genome and to identify individual genes within this sequence.
While the basic effort is of course a biological one, the description
and classification of sequences also lend themselves naturally to mathematical
and statistical modeling. This short textbook on the mathematics of genome
analysis presents a brief description of several ways in which mathematics
and statistics are being used in genome analysis and sequencing. It will
be of interest not only to students but also to professional mathematicians
curious about the subject.
**Contents**
Preface
1. Decomposing DNA
2. Recomposing DNA
3. Sequence statistics
4. Sequence comparison
5. Spatial structure and dynamics of DNA
Bibliography
Index.
Paperback: 139 pages
; 1st edition January 15, 2002;Cambridge University Press |