Gene Regulation and Metabolism: Post-Genomic Computational Approaches


Author(s): Julio Collado-Vides and Ralf Hofest"dt



  1. A brief history of genomics
  2. DNA array formats
  3. DNA array readout methods
  4. Gene expression profiling experimentsproblems, pitfalls and solutions
  5. Statistical analysis of array data: inferring changes
  6. Statistical analysis of array data: dimensionality reduction, clustering, and regulatory regions
  7. Survey of current DNA array applications
  8. Systems biology: overview of regulatory, metabolic and signaling networks

Cloth, 320 pages, 68 illus.; July 2002; MIT Press