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ISCBacademy is an online webinar series including the ISCB COSI, COVID webinars, Indigenous Voices and practical tutorials. We aim to inspire, connect, and communicate the science while providing a hands-on experience accessing and using newly developed bioinformatics tools while ensuring best practices for rigour and reproducibility.
June 24, 2025 at 11:00 AM EDT
Prebiotics and probiotics have shown promise as therapeutic interventions for improving cardiometabolic health, yet their effectiveness varies widely across individuals. This variability stems from the complex and heterogeneous nature of the human gut microbiome, as well as contextual factors like diet. We explore how metabolic modeling—an established framework for simulating microbial growth and function—can be leveraged to predict individualized responses to microbiome-targeted interventions. By modeling microbial metabolism at the community scale, we can begin to anticipate how specific prebiotic or probiotic strategies might influence both microbial composition and metabolite production, paving the way toward more precise and effective microbiome therapeutics.
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