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Results

July 22, 2025
8:40-9:00
Morning Welcome and Keynote Introduction
Track: Distinguished Keynotes

Room: 01A

Authors List: Show

July 22, 2025
9:00-10:00
Invited Presentation: Computational biology in the age of AI agents
Track: Distinguished Keynotes

Room: 01A

Authors List: Show

  • James Zou

Presentation Overview:Show

AI agents—large language models equipped with tools and reasoning capabilities—are emerging as powerful research enablers. This talk will explore how computational biology is particularly well-positioned to benefit from rapid advances in agentic AI. I’ll first introduce the Virtual Lab—a collaborative team of AI scientist agents conducting in silico research meetings to tackle open-ended research projects. As an example application, the Virtual Lab designed new nanobody binders to recent Covid variants that we experimentally validated. Then I will present CellVoyager, a data science agent that analyzes complex genomics data to derive new insights. Finally I will discuss using AI agents to discover and explain new biological concepts encoded by large protein foundation models (interPLM). I will conclude by discussing limits of agents and a roadmap for human researcher-AI collaboration.