| EMBO Practical Course: Measuring Translational Dynamics by Ribosome Profiling | |
|
Germany - Heidelberg |
|
| Hosted by: | EMBL Events |
| Venue: | EMBL Advanced Training Centre |
| Dates: | May 03, 2020 through May 09, 2020 |
|
Description |
|
| Regulation of translation is a key layer in the control of gene expression, playing a critical role in many biological and pathophysiological settings. In the last decade, methodological advances have provided comprehensive insights into cellular transcriptomes and proteomes, however, the systems-wide analysis of translation remained an unsolved experimental challenge. The recent advent of ‘ribosome-profiling’ has provided the methodological basis for comprehensive transcriptome-wide analyses of translation at sub-codon resolution by the precise and high-throughput determination of ribosomal positions on mRNA. Its application in a variety of organisms yielded novel insights into protein synthesis and its dynamic regulation, significantly advancing our understanding of the post-transcriptional regulation of gene expression. This practical course will combine theoretical sessions with hands-on experimentation and computation emphasising the key steps of the protocol and computational quality control. | |
| Additional Information | |
| Event URL: | https://www.embl.de/training/events/2020/MTD20-01/ |
| ISCB Member Discount: | None |
| Contact Person: | EMBL Events ([javascript protected email address]) |
While ISCB provides for conference and event listings that may be of interest to members and bioinformaticians at large, ISCB is not responsible for the content provided by outside sources. Such listings are not meant as an endorsement by ISCB.
