| Natural Genetic Engineering and Natural Genome Editing | |
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Austria - Salzburg - Salzburg |
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| Hosted by: | GenConText 2008 |
| Venue: | St.Virgil Conference Center |
| Dates: | Jul 03, 2008 through Jul 06, 2008 |
| Event Registration: | 2007-11-23 through 2008-03-31 |
| Early Registration Deadline: | 2007-12-31 |
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Description |
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| Over the past several years, the concept of natural genetic engineering has been advanced to encompass biochemical functions that make up the cellular toolbox for changing genome sequence composition and organization. Natural genetic engineering activities range from the introduction of point mutations by mutator polymerases to large-scale chromosome rearrangements mediated by transposable elements and non-homologous end-joining to incorporation of viral and microbial DNA into the genomes of host organisms. The recent literature on whole genome sequences provides abundant evidence for the action of natural genetic engineering in evolution. Discoveries about natural genetic engineering have coincided with rapid progress in our understanding of epigenetic control and RNA-directed chromatin formation. Both natural genetic engineering and chromatin formatting ("natural genome editing") exemplify the "read-write" potential of the genome as an information storage organelle. Special attention needs to be paid to the role of viruses and other so-called "parasitic" elements in the origin of genome formatting and natural genetic engineering capabilities. A critical question concerns the role of non-random genetic change operators in the production of complex evolutionary inventions. The purpose of the symposium is to bring together scientists working on genome organization, genome restructuring, genome formatting and virus research to discuss how we can integrate these discoveries into our basic understanding of evolution, development and disease. |
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| Additional Information | |
| Event URL: | http://www.naturalgenome.at |
| ISCB Member Discount: | None |
| Contact Person: | Dr. Hiltrud Oman ([javascript protected email address]) |
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