Day 4: Highlights & Recap!
With only one day left, ISMB 2022 gave us a day starting off with a stellar keynote, time to discover with exhibitors, and then dove right into 9 different tracks of science.
Highlights
Our fourth keynote address of the ISMB 2022 conference was from Dr. Ron Shamir, the ISCB Accomplishments by a Senior Scientist Award winner. Dr. Shamir’s talk was focused on the need for there to be a better understanding of disease. The current treatment methods in the medical field are a “one treatment fits all” approach, but what would be more beneficial to those in need of medical treatment, especially for cancer, would be a personalized diagnosis and a specific treatment tailored to the individual—and that is what Dr. Shamir’s research lab is hoping to better understand. They are aiming for a more intricate knowledge in basic science and medicine, with the goal of developing methods for personalized analysis. The suggested approach is for integrative methods, which will provide more robust findings overall, and allow for a more holistic and personalized solution to patient care and treatment.
Dr. Shamir’s lab has demonstrated the usefulness of integrated analysis through the development of algorithms, called Nemo and Domino, to detect similarities between cancers and detect crucial areas of active genes. There is also a focus on identifying driver genes specific to an individual, based on their personalized gene expression and mutation profiles—using an algorithm called Prodigy—with the hope of determining personalized treatment. A final aim of the research happening in Dr. Shamir’s lab is to be able to predict the risk a person has of developing cancer based on information gathered during routine checkups.
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