8th Annual Rocky Mountain Bioinformatics Conference


Updated Nov. 23, 2010



SomaLogic, Inc. is a privately-held biomarker discovery and clinical proteomics company based in Boulder, Colorado. The company's mission is to use its proprietary Slow-Offrate Modified Aptamer ("SOMAmer") technology to develop enhanced protein analysis tools and reagents for the life sciences community, to facilitate target validation, and to develop and commercialize clinical diagnostic products that will improve the delivery of healthcare by offering timely and accurate diagnostic information to physicians and their patients. Further information about SomaLogic can be found at www.somalogic.com.


Ion Torrent has pioneered an entirely new approach to sequencing that enables a direct connection between chemical and digital information. Ion Torrent™ technology doesn't use light—it's the first commercial PostLight™ sequencing technology.

Instead, Ion Torrent marries simple chemistry to incredibly powerful, proprietary semiconductor technology—it's Watson meets Moore. The result is a sequencing system that is simpler, faster, more cost effective and scalable than any other technology available. The company's goal is to democratize sequencing and make this critical technology available to every lab.

Ion Torrent sequencing technology requires no proprietary chemistries or optics because it's based on a well-characterized biochemical process. When a nucleotide is incorporated into a strand of DNA by a polymerase, a hydrogen ion is released as a byproduct. That hydrogen ion carries a charge which our proprietary ion sensor can detect. If a nucleotide, for example a C, is added to a DNA template and a signal is detected, you know that nucleotide was incorporated. Our sequencer—essentially the world's smallest solid-state pH meter—has called the base, going directly from chemical information to digital information. Because this is direct detection, each nucleotide incorporation is recorded in seconds and you can do an entire run in about an hour.

The semiconductor has transformed every industry it's touched. Just as the microprocessor enabled desktop computing to displace the mainframe, Ion Torrent semiconductor technology will inevitably democratize sequencing, putting it within the reach of any lab or clinic.