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Target Validation using Genomics and Informatics
United Kingdom - Hinxton, Cambridge

Hosted by: Wellcome Trust Scientific Conferences/EMBL
Venue: Wellcome Trust Genome Campus
Dates: Dec 08, 2015 through Dec 10, 2015

Call for Posters: 2015-07-07 through 2015-10-13
Event Registration: 2015-07-07 through 2015-11-03
 
Description
 
Wellcome Trust Scientific Conferences in association with EMBL is pleased to announce this new conference on Target Validation using Genomics and Informatics.

In the past few years, exceptional progress has been made in the application of genetics- and genomics-based technologies in biomedical research. There are currently thousands of DNA variants that are robustly associated with clinically relevant human traits. Although these should provide a rich source of molecular starting points for drug discovery, and a deeper understanding of their role in human physiology, the translation of these data from large-scale projects has been slow to influence the selection and validation of new targets in drug discovery and development programmes.

This meeting will bring together researchers based in academia and industry to focus on the opportunities and challenges for genomics in drug discovery. Epidemiology, molecular biology and computational approaches will be covered with a focus on contributions these methods can offer to the development of new therapies to treat patients.The potential of human cellular assays that can be perturbed genetically (by RNAi or CRISPR) or chemically will also be emphasised.

We welcome the submission of abstracts from all areas relevant to the main themes of the meeting. Several oral presentations will be chosen from the abstracts submitted.

Topics will include:
Common and rare diseases
Genetic epidemiology
Phenotypic screens
Functional studies
Target deconvolution
Cellular cohorts
Human knockouts
Informatics

Scientific programme committee
Ewan Birney EMBL-EBI, UK
Michael Ferguson University of Dundee, UK
Sally John Biogen, USA
Robert Plenge Merck, USA

Keynote speakers
Sally Davies Department of Health, UK
Mene Pangalos AstraZeneca, UK

Confirmed speakers
Jeff Barrett Centre of Therapeutic Target Validation, UK
John Danesh University of Cambridge, UK
George Davey Smith University of Bristol, UK
Edith Hessel GlaxoSmithKline, UK
Andrew Hopkins University of Dundee, UK
Daniel MacArthur Broad Institute of Harvard and MIT, USA
Mark McCarthy University of Oxford, UK
Mads Melbye National Health Surveillance and Research, Denmark
Nicole Soranzo Wellcome Trust Sanger Institute, UK
Richard Tremath King’s College London, UK
 
Additional Information
 
Event URL: https://registration.hinxton.wellcome.ac.uk/display_info.asp?id=522
ISCB Member Discount: None

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