| EMBO Practical Course: Measuring translational dynamics by ribosome profiling | |
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Germany - Heidelberg |
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| Hosted by: | European Molecular Biology Laboratory, EMBL Heidelberg |
| Venue: | EMBL Advanced Training Centre |
| Dates: | Mar 26, 2023 through Apr 01, 2023 |
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Description |
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| Regulation of translation is key in the control of gene expression, playing a critical role in many biological and pathophysiological settings. In the last decade, methodological advances have provided comprehensive insights into cellular transcriptomes and proteomes, however, the systems-wide analysis of translation remained an unsolved experimental challenge. The advent of ‘ribosome-profiling’ provided the methodological basis for comprehensive transcriptome-wide analyses of translation at sub-codon resolution by the precise and high-throughput determination of ribosomal positions on mRNA. Its application in a variety of organisms yielded novel insights into protein synthesis and its dynamic regulation, significantly advancing our understanding of the post-transcriptional regulation of gene expression. | |
| Additional Information | |
| Event URL: | https://www.embl.org/about/info/course-and-conference-office/events/mtd23-01/ |
| ISCB Member Discount: | None |
| Contact Person: | Aline Schnieder ([javascript protected email address]) |
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