| ISCBacademy - Pervasive downstream RNA hairpins dynamically dictate start-codon selection | |
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Virtual Event |
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| Hosted by: | ISCBacademy |
| Venue: | N/A |
| Dates: | Jan 30, 2024 through Jan 30, 2024 |
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Description |
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| Translation is a fundamental process in all biological kingdoms. The initiation of translation, which marks the outset of protein synthesis, is a highly regulated and crucial step. This initiation hinges on the recognition of the start codon by a scanning ribosome. Contrary to the conventional representation, more than half of mRNA molecules contain one or more upstream AUGs (uAUGs) before the primary AUG (mAUG). The presence of these uAUGs provides potential alternative sites for the ribosome to initiate translation before it reaches the mAUG. This diversity in start codon presence raises an intriguing question: How do eukaryotes dynamically select the appropriate start codon to initiate translation, especially when confronted with varying environmental conditions? | |
| Additional Information | |
| Event URL: | https://www.iscb.org/iscbacademy |
| ISCB Member Discount: | TBA |
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