9th Annual Rocky Mountain Bioinformatics Conference

Full Agenda

Updated Jan. 09, 2012

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Thursday – December 08, 2011
11:00 am – 1:00 pm Registration
1:00 pm – 1:45 pm Keynote 1
The Future of Research Communication: From Surfing to Deep Diving

Judith A. Blake, PhD

Associate Professor
The Jackson Laboratory
Bar Harbor, Maine - USA
1:45 pm – 1:55 pm Oral Presentation 1
The Rat Genome Curation: RGD Automated Data Integration Pipelines Maximize Coverage

Presenter: Marek Tutaj, Medical College of Wisconsin
Authors:
Marek Tutaj, Mary Shimoyama, Elizabeth Worthey, Jennifer Smith, Howard Jacob

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1:55 pm – 2:05 pm Oral Presentation 2
A Sensemaking Model for the Explorative Analysis of Large Gene Lists
Presenter:
Carsten Görg, University of Colorado Denver
Authors:
Carsten Görg, Barbara Mirel, Hannah Tipney

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2:05 pm – 2:15 pm Oral Presentation 3
The Role of p53 in Oligodendrocyte UPR
Presenter:
Hasan Jamil, Wayne State University
Author:
Hasan Jamil

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2:15 pm – 2:25 pm Oral Presentation 4
Quantitative Data: Where are they Hidden in Biomedical Literature?
Presenter:
Komandur Ravidumar, University of Colorado School of Medicine
Authors: K.E. Ravikumar, Meenakshi Narayanaswamy, S.V. Ramanan

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2:25 pm – 2:35 pm Oral Presentation 5
Multiscale Patient-Specific Blood Systems Biology

Presenter: Scott Diamond, University of Pennsylvania
Authors: Scott L. Diamond
2:35 pm – 2:45 pm Oral Presentation 6
A Resource for the Rational Selection of Drug Target Proteins and Leads for the Malaria Parasite, Plasmodium Falciparum
Presenter:
Fourie Joubert, University of Pretoria
Authors:
Jeanre Smit, Phele Mpangase, Michal Szolkiewicz, Misha le Grange, Fourie Joubert

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2:45 pm – 3:00 pm Break (15 minutes)
3:00 pm – 3:10 pm Oral Presentation 7
Identifying Treatment Relevant Colorectal Cancer Subtypes Using Iterative Non-negative Matrix Factorization
Presenter:
Andreas Schlicker, Netherlands Cancer Institute
Authors:
Andreas Schlicker, Garry Beran, Christine M Chresta, Gael McWalter, Alison Pritchard, Susie Weston, Sarah Runswick, Sara Davenport, Kerry Heathcote, Denis Alferez Castro, George Orphanides, Tim French, Lodewyk FA Wessels
3:10 pm – 3:20 pm Oral Presentation 8
The Origin of Mammalian Placentation Correlates with Protein Functional Shift and the Emergence of New Control Mechanisms
Presenter:
Mary O'Connell, Dublin City University
Authors:
Thomas A. Walsh, Kieran Holohan, Anna O'Brien, Robert Carton, Elinor Velasquez, Claire C. Morgan, Noeleen B. Loughran, Mary J. O'Connell
3:20 pm – 3:30 pm Oral Presentation 9
Exploring and Profiling Long Non-coding RNA in T Cell Development Using Next Generation Sequencing and Bioinformatics Approaches
Presenter:
Tzu L. Phang, University of Colorado Denver
Authors:
Tzu L. Phang, Ping Yao Zeng, Edwin.F. de Zoeten
3:30 pm – 3:40 pm Oral Presentation 10
Building an Interactome to Identify Signaling Components
Presenter:
Sarah Wyatt, Ohio University
Authors:
Sarah Waytt, Kaiyu Shen
3:40 pm – 3:50 pm Oral Presentation 11
GeneSmash: A RESTful Web Service for Gene Annotations
Presenter:
Ganiraju Manyam, University of Texas Anderson Cancer Center
Authors:
Michelle Payton, Ganiraju Manyam, Chris Wakefield, Jack Roth, Lynne Abruzzo, Kevin Coombes
3:50 pm – 4:00 pm Oral Presentation 12
Integrating Curated Databases and Text Mining Output into a Biomedical Knowledge Base
Presenter:
Kevin Livingston, University of Colorado Denver
Authors:
Kevin M. Livingston, Michael Bada, William A. Baumgartner Jr, Yuriy Malenkiy, Lawrence E. Hunter

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4:00 pm – 4:10 pm Oral Presentation 13
Using Evolving Protein Networks to Inform the Graph Coloring Problem
Presenter:
Todd Gibson, University of Colorado Denver
Authors:
Todd A. Gibson, Debra S. Goldberg
4:10 pm – 4:25 pm Break (15 minutes)
4:25 pm – 5:10 pm Keynote 2
Building Cell Maps: Status and Challenges

Emek Demir, PhD

Computational Biology Center
Memorial Sloan Kettering Cancer Center
New York, New York - USA
5:10 pm – 5:20 pm Oral Presentation 14
Machine Approaches to Recognition of Trypanosomal Variant Surface Glycoprotein Sequences
Presenter:
Jon Wilkes, Wellcome Trust Centre for Molecular Parasitology
Author:
Jon Wilkes

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5:20 pm – 5:30 pm Oral Presentation 15
Compact Encoding for Gene Therapy
Presenter:
Roger Hall, University of Arkansas at Little Rock
Author:
Roger Hall

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5:30 pm – 5:40 pm Oral Presentation 16
Microbial Monitoring and Space Exploration
Presenter:
Sven Bilke, NCI
Authors:
Sven Bilke, Verena Starke
5:40 pm – 5:50 pm Oral Presentation 17
CodingMotif: Exact Determination of Overrepresented Nucleotide Motifs in Coding Sequences
Presenter:
Jeffrey Chuang, Boston College
Authors:
Yang Ding, Andy Lorenz, Jeffrey Chuang

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5:50 pm – 6:00 pm Oral Presentation 18
GO Classes or Biclusters? Alternative Approaches for Exploring Microarray Probeset Subsets
Presenter:
George Acquaah-Mensah, Massachusetts College of Pharmacy and Health Sciences
Author:
George Acquaah-Mensah

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6:00 pm – 6:10 pm Oral Presentation 19
Accurate Inferring Transcription Regulation from a Compendium of Expression Profiles
Presenter:
Xueling Li, University of Texas, Medical Branch
Authors:
Xueling Li, Dirar Homouz, Andrzej Kudlicki

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6:10 pm – 6:20 pm Oral Presentation 20
A Proposed Algorithm for Epistasis Detection using Frequent Item-sets and Mutual Information

Presenter: James Rudd, North Carolina University
Author:
James Rudd, Assefa Tesfay, ClarLynda Williams-DeVane, Gaolin Zheng

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7:00 pm – 9:00 pm Banquet, Thursday, December 8, 2011
7:00 pm - 9:00 pm Banquet
Location: Il Poggio Restaurant, Snowmass Village
Note: The Dec 08 banquet has sold out. To be placed on a wait list, please email This email address is being protected from spambots. You need JavaScript enabled to view it..
>>> Go directly to: [Thursday - December 08] [Saturday - December 10]

Friday – December 09, 2011
9:00 am – 9:45 am Keynote 3
Project Halo: Constructing and Exploiting a Formal Representation of a Biology Textbook to Understand and Answer Users' Questions

Peter Clark, PhD

Vulcan Inc.
Seattle, Washington - USA
9:45 am – 9:55 am Oral Presentation 21
Molecular Insights to the Drug Resistance of V32I & M46L HIV-1 Protease Mutant to Inhibitor TMC114: Free Energy Calculation and Molecular Dynamics Simulations
Presenter:
Biswa Meher, Albany State University
Authors:
Biswa R. Meher, Yixuan Wang
9:55 am – 10:05 am Oral Presentation 22
Testing the Ortholog Conjecture with Functional Data from Several Pairs of Closely Related Organisms
Presenter:
Wyatt Clark, Indiana University
Authors:
Wyatt T. Clark, Predrag Radivojac, Matthew Hahn
10:05 am – 10:15 am Oral Presentation 23
Functional Profiling of Pharmacogenetic Non-synonymous SNPs
Presenter:
Chet Seligman, Buck Institute for Research on Aging
Authors:
Chet Seligman, Janita Thusberg, Jackson Miller, Emidio Capriotti, Jim Auer, Michelle Whirl-Carrillo, Teri Klein, Sean Mooney

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10:15 am – 10:25 am Oral Presentation 24
Limitations of Automated Annotation Software When Used with Draft Genomic Assemblies
Presenter:
Robert Norgren, University of Nebraska Medical Center
Author: Robert B. Norgren, Jr.

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10:25 am – 10:35 am Oral Presentation 25
Mixed Primary-Secondary Structure Alignment of ncRNA Covariance Models for Model Clustering and Combination
Presenter:
Jennifer Smith, Boise State University
Author:
Jennifer Smith

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10:35 am – 10:45 am Oral Presentation 26
In Silico Gene Expression Based Analysis on Claudin Family Members Association with Human Thyroid Cancer
Presenter: Shaukat Malik, Mohammad Ali Jinnah University
Authors: Shaukat Malik, S. Sameen, Z. Khalid
10:45 am – 11:00 am Break (15 minutes)
11:00 am – 11:10 am Oral Presentation 27
Data Management and Analysis Solutions for Meta-Analysis of Multi-Domain Data
Presenter:
ClarLynda Williams-Devane, North Carolina Central University
Authors:
ClarLynda Williams-DeVane, Archana Radadia, Nina Rountree, Stephen Edwards

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11:10 am – 11:20 am Oral Presentation 28
STOP and DEFOG: Web Applications for a Comprehensive Functional Gene Set Analysis
Presenter:
Tobias Wittkop, Buck Institute for Research on Aging
Authors:
Tobias Wittkop, Emily Teravest, Ari E. Berman, Uday Evani, K. Mathew Fleisch, Corey Powell, Nigam Shah, Sean D. Moone

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11:20 am – 11:30 am Oral Presentation 29
DAVID-WS: A Stateful Web Service to Facilitate Gene/Protein List Analysis
Presenter:
Xiaoli Jiao, NIH/NIAID
Authors:
Xiaoli Jiao, Brad T. Sherman, Da Wei Huang, Richard A. Lempicki

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11:30 am – 11:40 am Oral Presentation 30
Predicting Transcription Factor Binding Sites with Hidden Markov Models by using ChIP-Seq Data
Presenter:
Anthony Mathelier, University of British Columbia
Authors:
Anthony Mathelier, Wyeth W. Wasserman

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11:40 am – 11:50 am Oral Presentation 31
The Critical Assessment of Function Annotation Experiment: A Community-wide Effort Towards a Better Functional Annotation of Genes and Genomes
Presenter:
Predrag Radivojac, Indiana University
Authors:
Predrag Radivojac, Sean Mooney, Iddo Friedberg
11:50 am – 12:00 pm Oral Presentation 32
In Silico Rational Drug Design and Modeling Studies of Novel Inhibitors for Multi-target Inhibition in Pseudomonas Aeruginosa
Presenter:
Premkumar Jayaraman, Nanyang Technological University
Authors:
Premkumar Jayaraman, Lim Chu Sing Daniel, Meena K. Sakharkar

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12:00 pm – 12:30 pm Keynote 4
Advances in Protein Biomarker Discovery: Controlling for Sample Handling Artifacts and Confounding Effects

Mike Mehan, PhD
SomaLogic
Boulder, CO - USA
12:30 pm – 4:00 pm Break
4:00 pm – 4:45 pm Keynote 5
Deciphering of Human Protein Interactome using Structural Complexes

Anna Panchenko, PhD
Associate Investigator
National Center for Biotechnology Information
NLM, NIH
Bethesda, Maryland - USA
4:45 pm – 4:55 pm Oral Presentation 33
PathCMap: Development of Pathway Signature System for Identifying Druggable Partners of Synthetic Lethal Genes in Cancer
Presenter:
Jihye Kim, University of Colorado Denver School of Medicine
Authors:
Jihye Kim, Carlos H C Cano, Aik Choon Tan

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4:55 pm – 5:05 pm Oral Presentation 34
Identifying Single Copy Orthologs in Metazoa
Presenter:
Christopher Creevey, Teagasc
Authors:
Chris Creevey, Jean Muller, Tobias Doerks, Julie D. Thompson, Detlev Arendt, Peer Bork

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5:05 pm – 5:15 pm Oral Presentation 35
Mining Genomes to Understand the Origin of Vision in Metazoa
Presenter:
Davide Pisani, National University of Ireland, Maynooth
Authors:
Roberto Feuda, Davide Pisani
5:15 pm – 5:25 pm Oral Presentation 36
Evolutionary Pattern Embedded in the Lengths of Proteins and Their Structural Units
Presenter:
Minglei Wang, University of Illinois at Urbana-Champaign
Authors:
Minglei Wang, Cedric Debes, Frauke Gräter, Gustavo Caetano-Anollés
5:25 pm – 5:35 pm Oral Presentation 37
A Multiple-template Approach for Protein Threading
Presenter:
Jian Peng, Toyota Technological Institute at Chicago
Authors: Jian Peng, Jinbo Xu

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5:35 pm – 5:45 pm Oral Presentation 38
A New Probabilistic Model in Predictive Microbiology (NPMPM)
Presenter:
Nadine Schoene, Goethe University Frankfurt
Authors:
Nadine Schoene, Alexander Bockmayr, Bernd Appel, Annemarie Kaesbohrer

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5:45 pm – 8:00 pm Reception and Poster Session
Snowmass Conference Center (across street from Silvertree), Sinclair Room
>>> Go directly to: [Thursday - December 08] [Friday - December 09]

Saturday – December 10, 2011
9:00 am – 9:45 am Keynote 6
A New Day, A New High Performance Computer, What Does It Mean for the Life Sciences?

Kirk E. Jordan, PhD

Emerging Solutions Executive & Associate Program Director
Computational Science Center
IBM T.J. Watson Research
Member, IBM Academy of Technology
Massachusetts - USA
9:45 am – 9:55 am Oral Presentation 39
Rediscovery of the p53 Transcriptome
Presenter:
Mary Allen, University of Colorado
Authors:
Mary Allen, Robin Dowell, Joaquin Espinosa
9:55 am – 10:05 am Oral Presentation 40
Developing Maximum Likelihood and Bayesian Supertrees
Presenter:
Wasiu Akanni, National University of Ireland, Maynooth
Authors:
Wasiu Akanni, Davide Pisani, Peter Forster, Mark Wilkinson

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10:05 am – 10:15 am Oral Presentation 41
Prediction of Operons in Microbial Genomes by Integrating Diverse Information Sources
Presenter:
Anis Karimpour-Fard, University of Colorado Anschutz Medical Campus
Authors:
Anis Karimpour-Fard, Lawrence E. Hunter

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10:15 am – 10:25 am Oral Presentation 42
Gene Language Model
Presenter:
Siamak Rezaei, Talai
Author:
Siamak Rezaei

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10:25 am – 10:35 am Oral Presentation 43
Live and Let Die
Presenter:
Christian Forst, University of Texas Southwestern Medical Center
Authors:
Nassim Sohaee, Christian V. Forst
10:35 am – 11:05 am Keynote 7
SOMAmer-based Proteomic Analysis with Machine Learning


Hans Peter Graf, PhD
NEC Laboratories America, Inc.
Princeton, New Jersey - USA
11:05 am – 12:30 pm Poster Session
Snowmass Conference Center (across street from Silvertree)
Sinclair Room
12:30 pm – 4:00 pm Break
4:00 pm – 4:10 pm Oral Presentation 44
Broad Semantic Class Assignment for Biomedical Text
Presenter:
Kevin Bretonnel Cohen, University of Colorado School of Medicine
Authors:
K. Bretonnel Cohen, Thomas Christiansen, Lawrence E. Hunter
4:10 pm – 4:20 pm Oral Presentation 45
On the Accuracy of Protein Tertiary Structure Comparison
Presenter:
Aleksandar Poleksic, University of Northern Iowa
Authors:
Aleksandar Poleksic, Mauricio Arriagada
4:20 pm – 4:30 pm Oral Presentation 46
A Distributed Framework for Computation on the Results of Large Scale NLP
Presenter:
Christophe Roeder, University of Colorado, Anschutz Medical Campus
Authors:
Christophe Roeder, William Baumgartner Jr, Kevin Livingston
4:30 pm – 4:40 pm Oral Presentation 47
Probabilistic Search Frameworks for Protein Conformational Spaces
Presenter:
Amarda Shehu, George Mason University
Authors:
Amarda Shehu
4:40 pm – 4:50 pm Oral Presentation 48
Predicting HIV-1, Human Protein Interactome Through Indirect and Direct Evidences
Presenter:
Oznur Tastan, Microsoft Research New England
Authors:
Oznur Tastan, Jaime Carbonell, Judith Klein
4:50 pm – 5:00 pm Oral Presentation 49
Using Information Theory to Map Reads to a Reference Sequence
Presenter:
John Conery, University of Oregon
Author:
John Conery
5:00 pm – 5:45 pm Keynote 8
Transfer Function Analysis of Signal Transduction - The PSF System


Gabriele Scheler, PhD
Mountain View, California - USA

5:45 pm Rocky 2011 Closing Comments

>>> Go directly to: [Thursday - December 08] [Friday - December 09] [Saturday - December 10]