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What is Bioinformatics?

Whats BI 2013

Bioinformatics generally applies computer science to solve biological problems. However, the field is interdisciplinary and constantly developing, so it is difficult to answer this question in one sentence. 2012 and 2010-2011 articles have been archived. Earlier Archives are available.

General References

  • Fuller JC, Khoueiry P, Dinkel H, Forslund K, Stamatakis A, Barry J, Budd A, Soldatos TG, Linssen K, Rajput AM; HUB Participants.
    Biggest challenges in bioinformatics.
    EMBO Rep. 2013 Mar 15. PubMed abstract

  • Song M, Yang CC, Tang X.
    Detecting evolution of bioinformatics with a content and co-authorship analysis.
    Springerplus. 2013 Apr 26;2(1):186. PubMed abstract

  • Good BM, Su AI.
    Crowdsourcing for Bioinformatics.
    Bioinformatics. 2013 Jun 19. PubMed abstract

  • Hamada M.
    Fighting against uncertainty: an essential issue in bioinformatics.
    Brief Bioinform. 2013 Jun 26. PubMed abstract

  • Bernard V, Michaut M.
    Explain bioinformatics to your grandmother!
    PLoS Comput Biol. 2013 Oct;9(10):e1003305. PubMed abstract

Selected Topics

  • Dolled-Filhart MP, Lee M Jr, Ou-Yang CW, Haraksingh RR, Lin JC.
    Computational and bioinformatics frameworks for next-generation whole exome and genome sequencing.
    ScientificWorldJournal. 2013;2013:730210. PubMed abstract

  • Carrico J, Sabat A, Friedrich A, Ramirez M; on behalf of the ESCMID Study Group for Epidemiological Markers (ESGEM).
    Bioinformatics in bacterial molecular epidemiology and public health: databases, tools and the next-generation sequencing revolution.
    Euro Surveill. 2013 Jan 24;18(4). PubMed abstract

  • Rossi S, Calin GA.
    Bioinformatics, Non-coding RNAs and Its Possible Application in Personalized Medicine.
    Adv Exp Med Biol. 2013;774:21-37. PubMed abstract

  • Góngora-Castillo E, Buell CR.
    Bioinformatics challenges in de novo transcriptome assembly using short read sequences in the absence of a reference genome sequence.
    Nat Prod Rep. 2013 Apr;30(4):490-500. PubMed abstract

  • Hong H, Zhang W, Shen J, Su Z, Ning B, Han T, Perkins R, Shi L, Tong W.
    Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine.
    Sci China Life Sci. 2013 Feb;56(2):110-8. PubMed abstract

  • Caccia D, Dugo M, Callari M, Ongarzone I.
    Bioinformatics tools for secretome analysis.
    Biochim Biophys Acta. 2013 Feb 5. pii: S1570-9639(13)00050-2. PubMed abstract

  • Gromiha MM, Ou YY.
    Bioinformatics approaches for functional annotation of membrane proteins.
    Brief Bioinform. 2013 Mar 23. PubMed abstract

  • Ngounou Wetie AG, Sokolowska I, Woods AG, Roy U, Deinhardt K, Darie CC.
    Protein-protein interactions: switch from classical methods to proteomics and bioinformatics-based approaches.
    Cell Mol Life Sci. 2013 Apr 12. PubMed abstract

  • Tsongalis GJ, Chao E, Hagenkord JM, Hambuch T, Moore JH.
    Bioinformatics: What the Clinical Laboratorian Needs to Know and Prepare For.
    Clin Chem. 2013 May 30. PubMed abstract

  • Li MW, Qi X, Ni M, Lam HM.
    Silicon era of carbon-based life: application of genomics and bioinformatics in crop stress research.
    Int J Mol Sci. 2013 May 29;14(6):11444-83. PubMed abstract

  • Moriconi F, Beard MR, Yuen LK.
    Bioinformatics methods for the analysis of hepatitis viruses.
    Antivir Ther. 2013;18(3 Pt B):531-9. PubMed abstract

  • Hassanien AE, Al-Shammari ET, Ghali NI.
    Computational intelligence techniques in bioinformatics.
    Comput Biol Chem. 2013 Jul 10;47C:37-47. PubMed abstract

  • Kouskoumvekaki I, Shublaq N, Brunak S.
    Facilitating the use of large-scale biological data and tools in the era of translational bioinformatics.
    Brief Bioinform. 2013 Aug 1. PubMed abstract

  • Sun P, Ju H, Liu Z, Ning Q, Zhang J, Zhao X, Huang Y, Ma Z, Li Y.
    Bioinformatics resources and tools for conformational B-cell epitope prediction.
    Comput Math Methods Med. 2013;2013:943636. PubMed abstract

  • Sankar S, Nayanar SK, Balasubramanian S.
    Current trends in cancer vaccines - a bioinformatics perspective.
    Asian Pac J Cancer Prev. 2013;14(7):4041-7. PubMed abstract

  • Overby CL, Tarczy-Hornoch P.
    Personalized medicine: challenges and opportunities for translational bioinformatics.
    Per Med. 2013 Jul 1;10(5):453-462. PubMed abstract

  • Misra N, Panda PK, Parida BK.
    Agrigenomics for Microalgal Biofuel Production: An Overview of Various Bioinformatics Resources and Recent Studies to Link OMICS to Bioenergy and Bioeconomy.
    OMICS. 2013 Sep 17. PubMed abstract

  • Gu P, Chen H.
    Modern bioinformatics meets traditional Chinese medicine.
    Brief Bioinform. 2013 Sep 24. PubMed abstract

  • Choong YS, Tye GJ, Lim TS.
    Minireview: Applied Structural Bioinformatics in Proteomics.
    Protein J. 2013 Oct 6. PubMed abstract

  • Bencharit S, Border MB, Edelmann A, Byrd WC.
    Update in research and methods in proteomics and bioinformatics.
    Expert Rev Proteomics. 2013 Oct;10(5):413-415. PubMed abstract

  • Zhou S, Liao R, Guan J.
    When cloud computing meets bioinformatics: a review.
    J Bioinform Comput Biol. 2013 Oct;11(5):1330002. PubMed abstract

  • Naulaerts S, Meysman P, Bittremieux W, Vu TN, Vanden Berghe W, Goethals B, Laukens K.
    A primer to frequent itemset mining for bioinformatics.
    Brief Bioinform. 2013 Oct 26. PubMed abstract

  • Lopes RD, Resende NM, Honorio-França AC, França EL.
    Application of Bioinformatics in Chronobiology Research.
    ScientificWorldJournal. 2013 Sep 25;2013:153839. PubMed abstract

  • Huang X, Bruce B, Buchan A, Congdon CB, Cramer CL, Jennings SF, Jiang H, Li Z, McClure G, McMullen R, Moore JH, Nanduri B, Peckham J, Perkins A, Polson SW, Rekepalli B, Salem S, Specker J, Wunsch D, Xiong D, Zhang S, Zhao Z.
    No-boundary thinking in bioinformatics research.
    BioData Min. 2013 Nov 6;6(1):19. PubMed abstract


Links and references provided by Lynda Ellis