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  • RSG with DREAM 2020, Nov 16 - 19, 2020, Virtual ISCB Event
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  • ISCB-LA SoIBio BioNetMX 2020, Oct 28 – 29, 2020, Virtual Symposium
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 ISCBacademy Webinar Series
 
Mark your calendars for Wednesday, September 16, 2020!
 
Please use the link below to find more information or to register for:
 

September 16, 2020 at 12:00PM EDT, Encyclopedia of DNA Elements (ENCODE) Phase III by Zhiping Weng, hosted by ISCB

The human and mouse genomes contain instructions that specify RNAs and proteins and govern the timing, magnitude, and cellular context of their production. To better delineate these elements, phase III of the Encyclopedia of DNA Elements (ENCODE) Project has expanded analysis of the cell and tissue repertoires of RNA transcription, chromatin structure and modification, DNA methylation, chromatin looping, and occupancy by transcription factors and RNA-binding proteins. Here we summarize these efforts, which have produced 5,992 new experimental datasets, including systematic determinations across mouse fetal development. All data are available through the ENCODE data portal (https://www.encodeproject.org), including phase II ENCODE and Roadmap Epigenomics data. We have developed a registry of 926,535 human and 339,815 mouse candidate cis-regulatory elements, covering 7.9 and 3.4% of their respective genomes, by integrating selected datatypes associated with gene regulation, and constructed a web-based server (SCREEN; http://screen.encodeproject.org) to provide flexible, user-defined access to this resource. Collectively, the ENCODE data and registry provide an expansive resource for the scientific community to build a better understanding of the organization and function of the human and mouse genomes.

Hosted by:

The International Society for Computational Biology

 
 
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