EMBL-EBI and Head of Cellular Genetics at Wellcome Trust Sanger Institute
Hinxton, United Kingdom
Presentation Title: Understanding Cellular Heterogeneity
Time: Monday, July 11th, 4:40 pm - 5:40 pm
Introduction by: Christine Orengo
Room: Northern Hemisphere BCD, Dolphin Hotel
From techniques such as microscopy and FACS analysis, we know that many cell populations harbour heterogeneity in morphology and protein expression. With the advent of high throughput single cell RNA-sequencing, we can now quantify transcriptomic cell-to-cell variation. I will discuss technical advances and biological insights into understanding cellular heterogeneity in T cells and ES cells using single cell RNA-sequencing.Biography:
Sarah Teichmann is interested in global principles of protein interactions and gene expression. In particular, her research focuses on structural bioinformatics and biophysics of protein complexes, and genome biology to study genetic switches in T cells. Sarah did her PhD at the MRC Laboratory of Molecular Biology, Cambridge, UK and was a Beit Memorial Fellow at University College London. She started a group at the MRC Laboratory of Molecular Biology in 2001. In 2013, she moved to the Wellcome Trust Genome Campus in Hinxton/Cambridge, where her group is joint between the EMBL-European Bioinformatics Institute and the Sanger Institute. Sarah is an EMBO member and fellow of the Academy of Medical Sciences, and her work has been recognized by a number of prizes, including the Lister Prize, Biochemical Society Colworth Medal, Royal Society Crick Lecture and EMBO Gold Medal.
She is an ISCB’s vice-president, a member of its Board of Directors, and is active in the Conference and Education committees and the ISCB Students’ council. She served as the Chair of the European Conference in Computational Biology, and a member of the steering committees of RECOMB and ECCB.