Wednesday 25 – Friday 27 November 2026 · All times are CET (UTC+1)
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ELIXIR 3D-BioInfo Annual General Meeting (AGM) Wednesday 25 November, 12:00 CET → Friday 27 November, 12:30 CET The AGM runs from the opening reception on Wednesday to the closing session on Friday. Every session that is part of the AGM is marked with an orange bar on the left of the programme below. |
Wednesday 25 November 2026
| ELIXIR 3D-BioInfo AGM opens · 12:00 CET | |
| 12:00–13:30 | Reception and lunch |
| 13:30–14:00 |
Activity 1: Infrastructure and Protein Annotation
Scaling AI protein structure prediction to virology
Joe Grove
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| 14:00–14:30 |
Activity 1: Infrastructure and Protein Annotation
RIVET: attaching literature context to protein residues
Melanie Vollmar
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| 14:30–15:30 |
Activity 1: Infrastructure and Protein Annotation
Short talks
The Missense3D portal: bridging genomics with proteomics by leveraging protein structures for variant interpretation
Alessia David, Imperial College London
Towards Tunnelome: Unveiling the Functional and Pathogenic Landscape of Protein Tunnels in Proteome Scale
Anna Spackova, Palacký University Olomouc
Multimodal Geometric Deep Learning Reveals an Atlas of Catalytic Sites for the Human Proteoform
Jérôme Tubiana, Tel Aviv University
FAIRifying the ELIXIR 3D-BioInfo Protein-Protein Interface Benchmark for AI readiness
Emidio Capriotti, University of Bologna
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| 15:30–16:00 | Coffee break |
| 16:00–16:30 |
Activity 2: Complexes
Foldseek-Interface enables clustering of the resolved protein interface universe
Katja Luck
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| 16:30–17:00 |
Activity 2: Complexes
Solving 3D puzzles of biomolecular interactions by physics- and AI-based integrative modelling
Alexandre Bonvin
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| 17:00–18:00 |
Activity 2: Complexes
Short talks
Mapping the reliability domain of protein AI: what protein language models represent, and where their predictions fail
Structural Confidence Does Not Always Mean Structural Rigidity: Comparing AlphaFold pLDDT Scores with Experimental B-factors Across Disordered and Folded Proteins
The Gating Mechanism and Sodium Ion Transport in the Epithelial Sodium Channel
Fourth talk to be announced
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| 19:00 | Conference dinner at La Limonaia Ticketed event if registering for ELIXIR AGM only; included in full conference registration, reservation required |
Thursday 26 November 2026
| 09:00–09:30 |
Activity 3: Protein–ligand interactions
Invited speaker
Boltz and BoltzGen (title to be announced)
Jeremy Wohlwend, CSO, Boltz
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| 09:30–10:00 |
Activity 3: Protein–ligand interactions
Invited speaker
Assessing Boltz-2 Performance for the Binding Classification of Docking Hits
Prof. Didier Rognan, University of Strasbourg
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| 10:00–11:00 |
Activity 3: Protein–ligand interactions
Short talks
Virtual Kinome Assay: Fast, Scalable, and Interpretable Prediction of Kinome-Wide Binding Affinity Profiles
Elisa Lustrino, Sapienza University of Rome
Interrogating contrastive learning embeddings for structure-based virtual screening: a case study on DrugCLIP
Javier Sánchez Utgés, University College London
Deep Learning of Protein–Ligand Interaction Fingerprints Based on Functional Atom Matching for Drug Discovery and Protein Design
Christoph Manitz, Leipzig University / ScaDS.AI / KünzeLab – Institute for Drug Discovery, Leipzig, Germany
Structure-Based Fragment Growing Using Chemical Fragment Spaces
Christiane Ehrt, University of Hamburg, ZBH – Center for Bioinformatics, Germany
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| 11:00–11:30 | Coffee break |
| 11:30–12:30 |
ELIXIR session
Implementation Studies
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| END OF ELIXIR AGM | |
| 12:30–13:30 | Continuation of 3D-BioInfo 2026; lunch |
| 13:30–14:00 |
Activity 4: Nucleic Acid Structures
Title to be announced
Janusz Bujnicki
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| 14:00–14:30 |
Activity 4: Nucleic Acid Structures
Behind the Curtain: Exploring Hidden Molecular States of Nucleic Acids by Hyperpolarized NMR
Lukas Trantirek
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| 14:30–15:30 |
Activity 4: Nucleic Acid Structures
Short talks
CORAL: a dual-encoder cross-attention model that recovers RNA–protein interface geometry at residue and domain scale without structural supervision
Manuela Helmer-Citterich
ARIEL: An Openly Accessible Database of RNA–Ligand Binding Affinities with Experimental Structures
Mohit Chawla
LaRNAl: a web platform for RNA structure analysis
Maksim Serdakov
RNA-Puzzles: RNA 3D structure prediction in the past decade
Zhichao (Chichau) Miao
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| 15:30–16:00 | Coffee break |
| 16:00–16:30 |
Activity 5: Protein Engineering and Design
Functional peptide binder design beyond the natural amino acid space
Patrick Bryant
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| 16:30–17:00 |
Activity 5: Protein Engineering and Design
Title to be announced
Ora Schueler-Furman
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| 17:00–18:00 |
Activity 5: Protein Engineering and Design
Short talks
De novo design of inhibitors targeting Lassa virus infection
Florian Juhani Olander, Leipzig University, Medical Faculty, Institute for Drug Discovery
Structure-Guided Generative Design of Amyloid-Selective Antibody Candidates for Transthyretin Amyloidosis (ATTR)
Ugo Lomoio, Magna Graecia University of Catanzaro
Protein design for the inversion of metalloenzyme stereoselectivity
Cosimo Ciofalo, University of Florence
Much ado about nothing: modeling amino acid replacement with predicted protein structures
Lukas Buschmann, Dresden University of Technology (TU Dresden), ScaDS.AI
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| 18:00–19:00 | Poster session |
Friday 27 November 2026
| 09:00–09:30 |
3DSIG: Structural Bioinformatics and Computational Biophysics
Title to be announced
Gabor Erdos
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| 09:30–10:00 |
3DSIG: Structural Bioinformatics and Computational Biophysics
Title to be announced
Michael Heinzinger
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| 10:00–11:00 |
3DSIG: Structural Bioinformatics and Computational Biophysics
Short talks
Exploring the Universe of Zinc-Binding Proteins through Structure Prediction and Protein Language Models
Systematic Structural Characterization of Missense Mutations in Schizophrenia Risk Genes
PED 2026: a FAIR platform for integrative, machine-learning and proteome-scale ensembles of intrinsically disordered proteins
PIPENN-EMB ensemble net and protein embeddings generalise protein interface prediction beyond homology
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| 11:00–11:30 | Coffee break |
| 12:00–12:30 | Closing session |
Part of the ELIXIR 3D-BioInfo AGM
Programme subject to change. All times are Central European Time (CET, UTC+1).