Presentation Title: Next-generation Architecture for caBIG

Presentation slides (.pdf)

Abstract: The caBIG project now has 6+ years of experience with the challenges and benefits of defining, designing, developing, deploying, and evolving a distributed infrastructure to support collaborative data sharing across the translational medicine continuum.  As a direct result of both the successes of the first-generation of caBIG and the increasingly complex requirements of the caBIG stakeholder community around not only data sharing, but also more complex analytical and cross-process behavior coordination, the NCI Center for Biomedical Informatics and Information Technology (NCI CBIIT) has begun working on its next-generation architecture for caBIG.  This presentation will focus on a detailed enumeration of the distributed processing requirements for the next-generation of caBIG tools and technologies.  It will then discuss the core architecture strategies that have been adopted to satisfy these requirements.  Of particular importance is the adoption and adaption of a number of standards to support interoperability and automated decision making including such topics as management of cross-platform service-level security, ad hoc and distributed queries, and computationally assembled workflows.  In general, the overarching development strategy for the next-generation of caBIG is the combination of leveraging the experience gained and lessons learned both within the caBIG community over the last 6+ years, as well as in the larger internet community as it moves forward in its development of the Web 2.0 strategies, technologies, and tools.

Biography: Dr. Mead has over 35 years of experience in digital signal processing and algorithm development, complex software systems and architectures, and healthcare and life sciences informatics.  Dr. Mead has experience in clinical trials methodologies and data management systems, application of the Unified Process, and fundamental healthcare and life sciences informatics issues including terminology management, application of the Health Level Seven (HL7) Reference Information Model (RIM), use of Clinical Data Interchange Standards Consortium (CDISC) standards such as SDTM and ODM, the JANUS data model, and Oracle’s HTB development framework.  Dr. Mead currently is Chair of the HL7 Architecture Board, past-Chair of the Open Health Tools Architecture Project Team, and a current member of the CDISC Board of Directors.