| { C O N T E N T S } Volume 8, Issue 3
 
 President's 
              Letter Rost To BecomeNext ISCB President
 Rocky'05 BioinformaticsConference Colorado
 in December
 Update onPLoS Computational Biology
 
 Putting Students
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 Call for 2006Awards Nominations
 
 ISMB 2006 in Brazil
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              SiteNow Open
 ISMB 2006Call for Tutorials
 
 RECOMB 2006 Registration Opening This Week
 ISMB 2005 SIGs Recap
 Israeli Bioinformatics Symposium 
              2005
 A Prelude to ECCB’06
 
 Advertising & Corporate Membership 
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 Upcoming Events
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 News from the Field
 Acknowledgements 
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 | ISMB 
              2005 Special Interest Groups Meeting Recaps Seven Special Interest Groups (SIGs) met in conjunction 
              with ISMB 2005 in Detroit, Michigan, this past summer. Each year 
              ISCB invites select SIGs to share a summary of their meetings with 
              our readers as a means of potentially expanding awareness of their 
              work both during the conference and throughout the year. Below is 
              a recap of three such SIGs from 2005. 
 Automated Function Prediction 2005 SIG Summary Submitted by Iddo Friedberg, Martin Jambon and 
              Adam Godzik Automated function prediction is maturing into 
              a sub-field of its own within computational biology. On the one 
              hand, with all the data coming in from various genomics projects, 
              there is a dire need for annotation of genes and gene products. 
              On the other hand, the computational biology community has just 
              begun to recognize the need for bona fide automated annotators: 
              algorithms that are capable of receiving sequence or structure data 
              and producing a succinct function prediction, and doing so not only 
              by homology based methods. Furthermore, with the emerging predictors, 
              comes the need for assessment: how well are the function predictors 
              doing?  The first Automated Function prediction SIG meeting 
              was set up as focal point for the various research groups involved 
              in this new and exciting field. The 17 talks that were given discussed 
              the various aspects of computationally predicting function from 
              sequence, function from protein 3D structure, function from genomic 
              context, and the ways and means of assessing the quality of function 
              prediction programs. The response from leading researchers was extraordinary, 
              with Michael Sternberg from Imperial College delivering a keynote 
              talk, and Olivier Lichtarge (Baylor College of Medicine), Russ Altman 
              (Stanford University), Patricia Babbitt (UC San Francisco) and Adam 
              Godzik (The Burnham Institute) leading plenary sessions on predicting 
              function from structure, context based predictions, analysis of 
              function site, functional diversity, and challenging the servers. 
              Server challenge was done by Martin Jambon and Iddo Friedberg from 
              The Burnham Institute, and reported by Iddo Friedberg. A poster 
              session and lively discussions on the various aspects of this emerging 
              field served to enhance this exciting day. With 89 registrants and a head count of over 100 
              attendees, the one day meeting was considered extremely successful. 
              It was agreed that function prediction is indeed a distinct field, 
              and that there is a scientific community which is interested in 
              meeting regularly to discuss and develop it. Excerpts from the meeting 
              will be published in Protein Science in early 2006. More information 
              can be found at: http://ffas.burnham.org/AFP. 
 BioLINK 2005 SIG Summary Submitted by Christian Blaschke, 
              Kevin Cohen, Lynette Hirschman and Hagit Shatkay:BioLINK SIG co-organizers
 
 BioLINK SIG is concerned with the rapidly maturing field of biomedical 
              text mining: using techniques from natural language processing, 
              information extraction and information retrieval to automate knowledge 
              discovery from the biomedical literature and free text.
 
 This was the fifth consecutive BioLINK SIG at ISMB, and the first 
              time that it was held jointly with the Workshop on Linking Biological 
              Literature, Ontologies and Databases of the Association for Computational 
              Linguistics (ACL), whose annual conference took place in parallel 
              to ISMB in neighboring Ann Arbor. The joint meeting was the largest 
              BioLINK SIG so far (about 100 people in the audience), and attracted 
              many excellent full-length and short papers, posters and talks. 
              All papers, both long and short, went through a full peer-review 
              process. Eight full-length papers were accepted out of 18 full-paper 
              submissions; these were presented and published in the ACL Workshop 
              proceedings. Additionally, 9 short papers were accepted out of 21 
              short submissions and included in the SIG handouts; 5 of them were 
              selected for presentation during the workshop as short talks, for 
              a total of 13 research talks.
 
 The keynote speaker was Dr. Judith A. Blake, who is one of the leaders 
              of the Mouse Genome Informatics Group at the Jackson Laboratories 
              and a co-founder of the Gene Ontology Consortium. She presented 
              a fascinating talk about the current challenges of integrating biomedical 
              literature with bioinformatics and genomics information, to support 
              curation of model organism databases. This successful meeting concluded 
              with a lively poster session of 22 selected posters, followed by 
              dinner at Detroit’s Greek Town. We would like to thank the 
              many people who helped in organization and review, and particularly 
              Steven Leard for his outstanding organizational support for the 
              SIGs. We are looking forward to next year’s meeting in Brazil.
 
 Bioinformatics Open-Source Conference SIG 
              Summary
 Submitted by Darin London
 The Bioinformatics Open-Source Conference (BOSC) 
              is held annually as a Special Interest Group with the Intelligent 
              Systems for Molecular Biology (ISMB) conference, hosted by the Open 
              Bioinformatics Foundation (www.open-bio.org). 
              The aims of the conference are: to showcase the work of projects 
              devoted to creating open-source bioinformatics software, or open 
              standards of communication and information management; to facilitate 
              communication and interaction between developers working within 
              projects, and between project members and members of the wider community 
              interested in their projects; and educate the research community 
              on the value of open-source software and open standards. The meeting 
              consists of keynote speakers invited by the BOSC organizing committee 
              for outstanding achievements in Bioinformatics, Open-Source development, 
              or overall research skill; twenty-minute presentations selected 
              from a competetive pool of abstracts submitted for consideration; 
              five-minute lightning-talks and software demonstrations; and Birds 
              of a Feather meetings on specific projects or areas of interest. BOSC 2005 included two keynote speakers: Jason 
              Stajich, a key developer of the very popular BioPerl software package, 
              and Hilmar Lapp, speaking on behalf of the Open Bioinformatics Foundation. 
              Mr. Stajich's talk, 'Building Bioperl: lessons for Open-Source and 
              Bioinformatics', presented an historical summary of the development 
              of the BioPerl system, demonstrating the evolution of typical open-source 
              software projects, and the challenges they face. Dr. Lapp presented 
              the new organizational structure of the Open Bioinformatics Foundation 
              as a not-for-profit organization with memberships open to all those 
              who support their mission at no charge. All participants of BOSC 
              2005 were given the opportunity to becomemembers, and participate in shaping the future direction of the 
              foundation.
 The full length talk lineup included 15 speakers 
              whose abstracts were chosen from a very competitive group. They 
              demonstrate the diversity and quality of work being done in the 
              open-source bioinformatics community. Highlights include talks on 
              a variety of new tools for managing bioinformatics analyses, and 
              result visualization; discussions of a number of powerful data-mining 
              systems; and many tools designed to use or manage an ever expanding 
              list of web services for bioinformatics. The schedule for BOSC 2005, 
              including links to abstracts, images, and slides, can be accessed 
              at http://open-bio.org/bosc2005/finalProgram. Preparation for BOSC 2006 in Brazil is already 
              underway. Check the OBF website (www.open-bio.org) 
              for more details.
 
 
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