ISCB Fellows Keynote

Amos BairochAmos Bairoch (KN06)

Professor and Director, Department of Human Protein Sciences, University of Geneva; and
Group leader, Swiss Institute of Bioinformatics

Keynote's Website

Presentation Title: neXtProt 2015 highlights: SPARQL endpoint and biocuration efforts around the human protein variome
Date/Time: Tuesday, July 14th, 4:40 pm - 5:40 pm

Introduction by: Burkhard Rost




neXtProt ( allows you to efficiently query and retrieve knowledge on all human proteins. It complements the corpus of annotations from UniProtKB/Swiss-Prot with high-quality information originating from proteomics, transcriptomics and genomics technologies. Recently we have developed an advanced search engine based on RDF/SPARQL technology.

We are also soon going to integrate an in-house developed corpus of annotations relevant to the phenotypic effects of protein mutations in human diseases with an emphasis on cancers.



Professor of Bioinformatics and Director of the Department of Human Protein Science at the University of Geneva, Amos Bairoch is head of the CALIPHO group of the Swiss Institute of Bioinformatics. Until June 2009, Amos headed the Swiss-Prot group which develops the UniProtKB/ Swiss-Prot knowledgebase as well as PROSITE and ENZYME. He was also co-responsible for the development of ExPASy, the world’s first website dedicated to protein molecular biology. Amos Bairoch’s main work lies in the field of protein sequence analysis and the development of databases and software tools for this purpose. Currently his main activities are focused on the development of neXtProt, a web knowledge platform on human proteins. Amos Bairoch has been awarded several distinctions, among which the European Latsis Prize, the Otto Naegeli Prize and the HUPO Distinguished Achievement Award.