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UPCOMING DEADLINES & NOTICES

  • Presenter registration deadline (for talks and/or posters)
    BiGEvo 2025
    May 1, 2025
  • Last day for tutorial registration, if not sold out (You have until 23:59 CDT)
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    May 1, 2025
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    May 1, 2025
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    May 13, 2025
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    ISMB/ECCB 2025
    May 13, 2025
  • CAMDA extended abstracts submission deadline (for talks and/or posters) (You have until 23:59 Anywhere on Earth) *no extensions*
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    May 15, 2025
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    May 15, 2025
  • Deadline for submission
    INCOB 2025
    May 17, 2025
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    BiGEvo 2025
    May 19, 2025
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    May 19, 2025
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    May 20, 2025
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    May 22, 2025
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    May 22, 2025
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    May 26, 2025
  • Presentation schedule posted
    ISMB/ECCB 2025
    May 28, 2025
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Upcoming Conferences

A Global Community

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    The ISCB Affiliates program is designed to forge links between ISCB and regional non-profit membership groups, centers, institutes and networks that involve researchers from various institutions and/or organizations within a defined geographic region involved in the advancement of bioinformatics. Such groups have regular meetings either in person or online, and an organizing body in the form of a board of directors or steering committee. If you are interested in affiliating your regional membership group, center, institute or network with ISCB, please review these guidelines (.pdf) and send your exploratory questions to Diane E. Kovats, ISCB Chief Executive Officer (This email address is being protected from spambots. You need JavaScript enabled to view it.).  For information about the Affilliates Committee click here.

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Professional Development, Training, and Education

ISCBintel and Achievements

 2014 ISCB Overton Prize Award

Dana Pe'erDana Pe'er

Department of Biological Sciences and Systems Biology
Columbia University
New York, United States

website: http://www.c2b2.columbia.edu/danapeerlab/html/

Presentation Title: A multidimensional single cell approach TO understand cellular behavior

Presentation Time: Monday July 14,  4:45 pm - 5:45 pm

 

 

 

Abstract

High dimensional single cell technologies are on the rise, rapidly increasing in accuracy and throughput.  These offer computational biology both a challenge and an opportunity.   We will discuss a number of computational approaches to this data type and demonstrate a number of biological applications, including: (1) Using density estimation to characterize cellular signal processing in T-cell activation.  (2) New clustering and dimensionality reduction approaches to map heterogeneity between cells; with an application to characterizing tumor heterogeneity in Acute Myeloid Leukemia.  (3) An algorithm to order cells according to their developmental maturity and its use to identify novel progenitor B-cell sub-populations.

 

Biography

Dana Pe’er is an associate professor in the Departments of Biological Sciences and Systems Biology. Our team develops computational methods that integrate diverse high-throughput data to provide a holistic, systems-level view of molecular networks. Currently we have two key focuses: developing computational methods to interpret single cell data and understand cellular heterogeneity; Modeling how genetic and epigenetic variation alters regulatory network function and  subsequently phenotype in health and disease.  This path has led us to explore how systems biology approaches can be used to personalize cancer care.  Dana is recipient of the Burroughs Wellcome Fund Career Award, NIH Directors New Innovator Award, NSF CAREER award, Stand Up To Cancer Innovative Research Grant and a Packard Fellow in Science and Engineering.

 

Michal Linial, PhD

Director of The Sudarsky Center for Computational Biology
Department of Biological Chemistry
Institute of Life Sciences
The Hebrew University of Jerusalem, Israel

website: http://www.ls.huji.ac.il/michall/

Presentation Title: TBA

Presentation Time: Sunday July 13,  9:00 - 10:00



 

Abstract:

TBA

Biography:

Michal Linial is a Professor of Biochemistry, Molecular Biology and Bioinformatics at the Hebrew University of Jerusalem, Israel, where she heads the Israel Institute for Advanced Studies.

She received her PhD from the Hebrew University's Medical School (1986) in Biochemistry and Molecular Biology. During her post-doctoral training in Stanford University, she engaged in molecular neuroscience with the goal of deciphering the molecular makeup of the synapse. She joined the Hebrew University (1989) and was a driving force in merging computational and analytical tools with classical wet biology. She is a founder (1999) and the chair of the undergraduate and graduate joint program in Computer sciences and Life Sciences at the Hebrew University. She heads The Sudarsky Center for Computational Biology at the Hebrew University.

Her laboratory is active in the two arenas - She leads a wet lab as well as a computational group. Her research interests span a broad range of topics such as stem cells, neuronal differentiation, synapse regulation, cell biology of secretory systems and the molecular mechanisms that underlie behavior and metabolic diseases. With the maturation of large-scale technologies, she has become involved in developing methods for target selection in Structural Genomics, protein family classification and the development of methodologies for the analysis of large-scale biological data sets. She is particularly interested in introducing powerful computational tools to meet the needs of the biological and bio-medical research communities. Among the web tools developed by her research group are PANDORA, ProtoNet, and EVEREST. One of her main recent areas of activity is proteomics where she combines experimental, technological and computational work.

She is an ISCB’s vice-president, a member of its Board of Directors, and is active in the Conference and Education committees and the ISCB Students’ council. She served as the Chair of the European Conference in Computational Biology, and a member of the steering committees of RECOMB and ECCB.


Isaac (Zak) Kohane MD, PhDZac Kohane
Director, Children’s Hospital Informatics Program
Henderson Professor of Pediatrics and Health Sciences and Technology
Harvard Medical School and Children’s Hospital Boston
Director, Countway Library of Medicine
Director, i2b2 National Center for Biomedical Computing
Co-Director, HMS Center for Biomedical Informatics

website: http://www.childrenshospital.org/cfapps/research/data_admin/Site113/mainpageS113P0.html

Presentation Title: TBA

Presentation Time: Monday July 14,  9:00 am - 10:00 am

 

Abstract

TBA


Biography

Isaac (Zak) Kohane is the director of the Children’s Hospital Informatics Program and is the Henderson Professor of Pediatrics and Health Sciences and Technology at Harvard Medical School (HMS). He is also the co-Director of the HMS Center for Biomedical Informatics and Director of the HMS Countway Library of Medicine. Dr. Kohane leads multiple collaborations at Harvard Medical School and its hospital affiliates in the use of genomics and computer science to study diseases (particularly cancer and autism) through the perspective of biological development. He also has developed several computer systems to allow multiple hospital systems to be used as “living laboratories” to study the genetic basis of disease while preserving patient privacy. Among these, the i2b2 (Informatics for Integrating Biology and the Bedside) National Computing Center has been deployed at over 52 academic health centers internationally.

Dr. Kohane has published over 200 papers in the medical literature and authored a widely used book on Microarrays for an Integrative Genomics. He has been elected to multiple honor societies including the American Society for Clinical Investigation, the American College of Medical Informatics, and the Institute of Medicine. He leads a doctoral program in genomics and bioinformatics at the Division of Health Sciences and Technology at Harvard and MIT. He is also a practicing pediatric endocrinologist and father of three energetic children.

Tutorials Program

ISMB 2014 will feature two (2) half-day tutorial sessions on Saturday, July 12, 2014 one day prior to the conference scientific program. Tutorials are held on the same day as the second day of the SIGs and Satellite meetings.

 
Tutorial attendees will be able to register using the on-line registration system. Tutorial participants must be registered for the ISMB conference to attend a tutorial. Attendees will receive a Tutorial Entry Pass (ticket) at the time they register on site. Tutorial handouts and electronic notes can be picked up at on-site registration desk at the Hynes Convention Centre. Lunch is included in the registration fee for attendees registering for two tutorials. Those attending one tutorial only have the option to purchase a lunch ticket during on-line registration.
 

Tutorial 1:  Computational Metagenomics Techniques and Challenges

July 12, 2014
8:30 am - 12:30 pm
Location: Hynes Convention Center
Room: TBD

 

Presenters:
Curtis Huttenhower, Harvard School of Public Health, Boston, United States
Titus Brown, Michigan State University, East Lansing, United States

 

Microbial ecology is one of many fields that have benefitted greatly from technical advances in DNA sequencing. In particular, low-cost culture-independent sequencing has made metagenomic and metatranscriptomic surveys of microbial communities practical, including bacteria, archaea, viruses, and fungi associated with the human body, other hosts, and the environment. The resulting data have stimulated the development of many new computational approaches to meta'omic sequence analysis, including metagenomic assembly, microbial identification, and gene, transcript, and pathway metabolic profiling.
 
We will present a high-level introduction to computational metagenomics, highlighting the state-of-the-art in the field as well as outstanding challenges. These include an introduction to the biological goals of typical meta'omic studies and the bioinformatic processes currently available to achieve them. This will briefly summarize the major aspects of metagenomics analysis to be covered here: reference genome-based community composition and functional profiling, along with methods for constructing new genomic references by using de novo assembly. We will discuss the challenges associated with precisely quantifying members of a microbial community and functional analysis of the gene families in a community, the association of those gene families with their source organisms, and the combination of gene families into pathways for metabolic profiling. Finally, as sequencing technologies deliver more data for the same price, our ability to examine complex microbial communities using sequencing grows. For environmental communities, many fewer reference genomes or transcriptomes are typically available than for human-associated microbes, and the substantial diversity of many communities means that terabases of sequencing may be needed to recover a significant fraction of the community metagenome.  We will discuss our growing body of work on large-scale de novo assembly, reference free methods for investigating community coverage, and diversity estimation for shotgun sequencing data.  The tutorial will include standardized protocols for microbial profiling, functional profiling, and metagenome/metatranscriptome assembly with benchmarks and examples.
 

Segata N, Boernigen D, Tickle TL, Morgan XC, Garrett WS, Huttenhower C. "Computational meta'omics for microbial community studies." Mol Syst Biol 2013, http://www.ncbi.nlm.nih.gov/pubmed/23670539

Pell J, Hintze A, Canino-Koning R, Howe A, Tiedje JM, Brown CT. "Scaling metagenome sequence assembly with probabilistic de Bruijn graphs." PNAS 2012, http://www.ncbi.nlm.nih.gov/pubmed/22847406

 

Note: Please bring your own laptop to the tutorial.

 

Tutorial 2: Wikipedia: WikiProject Computational Biology/ISMB 2014

July 12, 2014
1:30 pm - 4:30 pm
Location: Hynes Convention Center
Room: TBD

 

Presenters:
Daniel  Mietchen, Museum für Naturkunde Berlin, Germany
Ben Moore, University of Edinburgh, Scotland
WikiProject Computational Biology

In this tutorial, we will provide a practical introduction to editing Wikipedia for scientists. By the end of the course, participants will understand the basics of editing and have made actual contributions to Wikipedia articles. Each participant will be required to bring some pre-prepared written material, images or multimedia files to add to an article of their choice in any language version of Wikipedia. In addition, we will teach the participants about the etiquette of being a Wikipedia editor as well as helping them to avoid some of the pitfalls that new editors sometimes come across. We will also introduce the PLOS Computational Biology Topic Pages destined for the English Wikipedia, inform about the ISCB Wikipedia Competition and provide an overview of some of the sister platforms of Wikipedia, notably Wikidata and Wikimedia Commons, and their coverage of Computational Biology.

 

Note: Please bring your own computer and prepare some materials for you to add to Wikipedia during the tutorial

Level: General

 

Special Interest Groups (SIGs) & Satellite Meetings (SMs)

*Attention poster presenters: The ideal poster size should be a maximum of 0.90 m (wide) x 1.20 m (high). View an image of the poster board here.

 

Satellite Meetings

SIGS (Special Interest Groups)

One-Day SIGs – Friday, July 10, 2015

Integrative RNA Biology SIG (IRB-SIG)

NetBio SIG

 

One-Day SIGs – Saturday, July 11, 2015

Automated Function Prediction (AFP-SIG)

Regulatory Genomics Special Interest Group (RegGenSIG)

VarI SIG

 

Two-Day SIGs – Friday, July 10 and Saturday, July 11, 2015

Bio-Ontologies

BioVis SIG

BOSC:16th Annual Bioinformatics Open Source Conference

HitSEQ: High Throughput Sequencing Algorithms & Applications

 

 

Satellite Meetings

3Dsig: Structural Bioinformatics & Computational Biophysics

URL: http://bcb.med.usherbrooke.ca/3dsig15/

Date: Friday, July 10 & Saturday, July 11

Start Time: 8:30 a.m - 6:00 p.m.

Room: Liffey Hall 1

 

3Dsig Structural Bioinformatics & Computational Biophysics has become the largest meeting in this growing field. This year we are celebrating our 11th meeting and highlighting the 2013 Nobel prize in Chemistry awarded to Martin Karplus, Michael Levitt & Arieh Warshel, the pioneers of the field. Nobel Laureate Michael Levitt will give the main after-dinner talk. In addition, our keynotes include Amadeo Caflisch, Guido Capitani, William DeGrado, Lucy Forrest, Des Higgins, Lynn Kamerlin, Sarah Teichman and Harel Weinstein.

In addition to keynotes our diverse program will include 20 talks selected from submitted abstracts, laptop software demos and poster sessions. Simply put, 3DSIG is the most comprehensive conference in the field and should not be missed by anyone using macromolecular structure to computationally unravel the mysteries of living systems.

Over the years, 3DSig has brought the leaders of the field of Structural Bioinformatics and Computational Biophysics in an ideal environment for personal contacts and discussions. The list of past keynotes includes: Russ Altman, Patricia Babbitt, Ivet Bahar, Nir Ben-Tal, Tom Blundell, Phil Bourne, James U. Bowie, Steven Brenner, Steve Bryant, Janusz Bujnicki, Stephen Burley, Wah Chiu, Cyrus Chothia, Charlotte Deane, Roland Dunbrack, Keith Dunker, Aled Edwards, Arne Elofsson, Stephen Friend, Dmitrij Frishman, Adam Godzik, David Goodsell, Nick Grishin, Kevin Karplus, Amy E. Keating, Tanja Kortemme, Gunnar von Heijne, Barry Honig, David Jones, Thomas Lengauer, Michael Levitt, Olivier Lichtarge, Andrei Lupas, François Major, George I. Makhatadze, Debora Marks, John Moult, Klaus Mueller, Masha Niv, Ruth Nussinov, Arthur Olson, Christine Orengo, Robert Preissner, Burkhard Rost, Rob Russell, Andrej Sali, Chris Sander, Jeffrey Saven, Tamar Schlick, Torsten Schwede, Luis Serrano, Brian Shoichet, Michael Schroeder, Kim A. Sharp, Jeffrey Skolnick Manfred Sippl, Michael Sternberg, Raymond Stevens, Joel Sussman, Devarajan Thirumalai, Janet Thornton, Anna Tramontano, Ron Unger, Alfonso Valencia, Sandor Vajda, Rebecca Wade, Haim Wolfson, Ada Yonath.

Abstract submission deadline: April 30, 2015

Relevant topics are listed in http://bioinformatics.oxfordjournals.org/content/31/1/146.long
These include:

  • Macromolecular (tertiary and quarternay) structure prediction.
  • Application of structure to systems biology and vice versa.
  • Structure-based drug discovery including polypharmacology and network pharmacology.
  • Structure representation, classification and prediction.
  • Macromolecular assemblies and multi-domain protein structures.
  • Structural genomics.
  • 3D databases and data mining including integration and accessibility of methods and databases.
  • Molecular visualization.
  • Relevant methods of structure determination, particularly hybrid methods.
  • Structure-based function prediction.
  • Evolution Studied through structures and evolution (e.g. correlated mutations) utilized to predict and study structures
  • Docking, analysis, prediction and simulation of biomolecular interactions such as protein-protein, protein-ligand and protein-nucleic acid.
  • Chemical systems biology and small molecule docking simulations.
  • Prediction and analysis of protein domains.
  • Membrane protein structure analysis and prediction.
  • Protein dynamics and disorder
  • The structural basis of immunology.
  • 3D RNA structures
  • Protein engineering and synthetic biology.

We look forward to meeting you at 3Dsig

 

Philip E. Bourne (chair)
Associate Director for Data Science, National Institutes of Health, Bethesda, United States
This email address is being protected from spambots. You need JavaScript enabled to view it.


Rafael Najmanovich
Université de Sherbrooke, Canada
This email address is being protected from spambots. You need JavaScript enabled to view it. 

Ilan Samish
The Weizmann Institute of Science; and
Braude College of Engineering, Israel
This email address is being protected from spambots. You need JavaScript enabled to view it.

 

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CAMDA 2015 Critical Assessment of Massive Data Analysis

URL: http://www.camda.info
Date: Friday, July 10 & Saturday, July 11

Start Time: 8:30 a.m - 6:00 p.m.

Room: Wicklow Meeting Room 2

The emergence of Big Data in the life sciences is considered one of the grand challenges of our time. The interpretation of large data sets is now one of the scientific key techniques in the post genomic era. Still the data analysis bottleneck limits genome scale experiments in providing new medical and biological insights at a larger scale. This trend towards the need for analysing massive data sets is further accelerated by novel high throughput sequencing technologies and the increasing size of biomedical studies.

CAMDA focuses on the analysis and integration of the massive data sets now prevalent in the life sciences. It introduces new approaches and solutions to the Big Data problem, and presents new techniques in the field of bioinformatics, data analysis, and statistics for handling and processing challenging large data sets. By discussing cutting-edge problems and opportunities, the conference offers researchers from a wide range of fields a unique opportunity to benefit from a critical comparative evaluation of approaches to exploiting Big Data in the life-sciences.

This year, the scientific committee of CAMDA has set three data analysis contest challenges:

  1. A toxicogenomics study with matched NGS and microarray profiles for the response of over 100 rat livers to 27 chemicals with 9 different modes of action.
  2. A synthetic reference benchmark with built-in truths, spanning multiple NGS, microarray, and qPCR platforms from the FDA SEQC.
  3. A selection of large-scale cancer studies of less well-understood diseases from the latest release of the International Cancer Genome Consortium (ICGC), including matched gene and microRNA expression profiles from RNA-Seq, somatic CNV, methylation, and protein expression profiles.


We cordially invite you to attend this year's CAMDA in Dublin!

Keynotes:
Des Higgins, University College Dublin, Ireland (confirmed)
Gaddy Getz, Broad Institute, Boston (t.b.c.)

Key dates:

  • May 20, 2015 - Extended Abstract Proposals Due
  • May 25, 2015 - Abstract Deadline for Poster Submission
  • May 30, 2015 - Notification of Accepted Contributions
  • June 6, 2015 - Early Registration Closes
  • July 10 & 11, 2015 - CAMDA 2015
  • Aug 25,  2015 - Full Paper Submission


Organizers:
Djork-Arné Clevert, JKU Linz, Austria
Joaquin Dopazo, CIPF, Spain
Lan Hu, Exosome Diagnostics, Cambridge, MA, USA
David Kreil, Boku University Vienna, Austria

Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

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SIG Meetings
 

Automated Function Prediction (AFP-SIG)

URL: http://biofunctionprediction.org/

Date: Saturday, July 11

Start Time: 8:30 a.m - 6:00 p.m.

Room: Ecocem Room

The accurate annotation of protein function is key to understanding life at the molecular level. However, with its inherent difficulty and expense, experimental characterization of function cannot scale up to accommodate the vast amount of sequence data already available. The computational annotation of protein function has therefore emerged as a problem at the forefront of bioinformatics. Recently, the availability of genomic-level sequence information for thousands of species, coupled with massive high-throughput experimental data, has created new opportunities as well as challenges for function prediction. Many methodologies have been developed by research groups worldwide, many based in comparing unsolved sequences with databases of proteins whose functions are known. Other methods aim at mining the scientific literature associated with some of these proteins, yet others combine sophisticated machine-learning algorithms with an understanding of biological processes to decipher what these proteins do.

The mission of the Automated Function Prediction Special Interest Group (AFP-SIG) is to bring together computational biologists, experimental biologists and biocurators who are dealing with the important problem of gene and gene product function prediction, to share ideas and create collaborations. The AFP-SIG holds annual meetings alongside the ISMB. Also, we are conducting the multi-year Critical Assessment of protein Function Annotation, or CAFA, experiment.
Talks are sought in, but not limited to, the following topics:

  • Function prediction using sequence based methods. This would include "classic" methods such as detection of functional motifs and inferring function from sequence similarity.
  • Function from genomic information: prediction by genomic location; locus comparison with other organisms; function gain and loss.
  • Phylogeny based methods
  • Function from molecular interactions
  • Function from structure
  • Function prediction using combined methods
  • "Meta-talks" discussing the limitations and horizons of computational function prediction.
  • Assessing function prediction programs

 

Key Dates:

  • March 1, 2015: Call for abstracts (talks & posters) opens
  • April 6, 2015: Deadline for submitting abstracts
  • May 9, 2015: Authors notified of abstract status
  • July 11, 2015: AFP/CAFA 2015, Dublin, Ireland
  • July 10-15, 2015: ISMB 2015, Dublin, Ireland


Keynote speaker: Ioannis Xenarios, Swiss Institute of Bioinformatics.

Organizers:
Predrag Radivojac, Indiana University, USA This email address is being protected from spambots. You need JavaScript enabled to view it.
Sean Mooney, Buck Institute for Research on Aging, USA  This email address is being protected from spambots. You need JavaScript enabled to view it.
Mark Wass Kent University, UK This email address is being protected from spambots. You need JavaScript enabled to view it.
Iddo Friedberg, Miami University, Oxford OH USA This email address is being protected from spambots. You need JavaScript enabled to view it.

 

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Bio-Ontologies

URL: http://www.bio-ontologies.org.uk

Date: Friday, July 10 & Saturday, July 11

Start Time: 8:30 a.m - 6:00 p.m.

Room: Wicklow Meeting Room 1

The Bio-Ontologies SIG provides a forum for discussion of the latest and most innovative research in the appplication of ontologies and more generally the organisation, presentation and dissemination of knowledge in biomedicine and the life sciences. Bio-Ontologies has existed as a SIG at ISMB for 18 years, making it one of the longest running.
 
Key Dates

  • April 10th, 2015 Submissions Due
  • May 8th, 2015 Notifications
  • May 15th, 2015 Final Version Due


The 2015 meeting will be a two day SIG, with July 11th being the “Phenotype Day”.  Papers are invited in areas, such as the applications of bio-ontologies, newly developed bio-ontologies, and the use of ontologies in data sharing standards. Example topics include (but not limited to):
 
Applications of ontologies in bioinformatics
Hypothesis Testing Platforms
Use of Ontologies in Phenotype representation
"Flash updates" on Newly Developed or Existing Bio-Ontologies
Bio-Curation Platforms
Automated Annotation Pipelines
Efforts using ontologies for Bio-NLP or Information Retrieval
Semantic Web Enabled Applications
Role of Bio-Ontologies in Health 2.0
 
Advances in development of biomedical ontologies
Collaborative Ontology Authoring and Peer-Review Mechanisms
Automated Ontology Learning
Mapping between Ontologies
Research in Ontology Evaluation
Using games for Ontology review and evaluation
 
Organizers:
Nigam Shah, Stanford University, United States,This email address is being protected from spambots. You need JavaScript enabled to view it.
Michel Dumontier, Stanford University, United States,This email address is being protected from spambots. You need JavaScript enabled to view it.
Larisa Soldatova, Brunel University, United Kingdom,This email address is being protected from spambots. You need JavaScript enabled to view it.
Philippe Rocca-Serra, University of Oxford, United Kingdom,This email address is being protected from spambots. You need JavaScript enabled to view it.
 
Phenotype Day co-ordinators: Nigel Collier, Anika Oellrich, Tudor Groza, and Karin Verspoor
 
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

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BioVis SIG: 5th Symposium on Biological Data Visualization

URL: http://biovis.net

Date: Friday, July 10 & Saturday, July 11

Start Time: 8:30 a.m - 6:00 p.m.

Room: Wicklow Hall 1

The rapidly expanding field of biology creates enormous challenges for the computational visualization techniques that are necessary in order to enable researchers to gain insight from their large and highly complex data sets.

The Symposium on Biological Data Visualization (BioVis) is the premier international and interdisciplinary event for all aspects of visualization in biology. The symposium brings together researchers from the visualization, bioinformatics, and biology communities with the purpose of educating, inspiring, and engaging visualization researchers in problems in biological data visualization, as well as bioinformatics and biology researchers in state-of-the-art visualization research. The symposium serves as a platform for researchers from these fields to increase the impact of data visualization approaches in biology. The breadth and diversity of biological research topic areas will enable researchers from all parts of the visualization and bioinformatics communities to contribute to this effort and the symposium will provide an excellent opportunity to initiate interdisciplinary collaborations.

Keynote speaker:

Torsten Möller, Research Group Visualization and Data Analysis, University of Vienna, Austria
Lawrence Hunter , Director of the University of Colorado's Computational

 

1) Papers:
We are soliciting high-quality papers that will go through a rigorous peer-review, and will be published either in BMC Bioinformatics or BMC Proceedings and be orally presented at the symposium; accepted highest-quality papers will be published in the BMC Bioinformatics journal, accepted papers that feature high quality but are not accepted for BMC Bioinformatics will be published in BMC Proceedings (for details see http://biovis.net/year/2015/papers)

2) Posters:
We seek work in progress and preliminary results; previously published work from other venues; visualization challenges (for details see http://biovis.net/year/2015/posters). Submissions consist of a 250 abstract and an image;

3) Data Contest:
We are soliciting visualizations or visualization tools that would help biologists develop hypotheses about what features of the RNA molecules described by the "observed" sequences are important to their function; submit a 2-page extended abstract (for details see http://biovis.net/year/2015/data-contest)

4) Design Contest:
Please submit a designed figure utilizing effective encodings and clear visual communication to display better representations for RNA structures (for details see http://biovis.net/year/2015/design-contest)
Note that the data and design contest are highly connected and a combined submission is also welcome.

Key Dates: (all deadlines are 5:00pm PDT)

  • February 15, 2015 – Paper submission
  • May 1, 2015   - Submission deadline for the Data Contest
  • May 1, 2015   - Submission deadline for the Design Contest
  • May 29, 2015  - Poster abstract submission


Organizing Committee members:
General chairs:
 - Kay Nieselt, University of Tübingen, Germany, This email address is being protected from spambots. You need JavaScript enabled to view it.
 - G. Elisabeta Marai, University of Illinois at Chicago, USA, This email address is being protected from spambots. You need JavaScript enabled to view it.

 For the full committee, see http://biovis.net/year/2015/info/committee.

 

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BOSC: 16th Annual Bioinformatics Open Source Conference

URL: http://www.open-bio.org/wiki/BOSC_2015

Date: Friday, July 10 & Saturday, July 11

Start Time: 8:30 a.m - 6:00 p.m.

Room: Wicklow Hall 2A

The Bioinformatics Open Source Conference (BOSC) is run as a two-day meeting before the annual ISMB conference. It is sponsored by the Open Bioinformatics Foundation (O|B|F), a non-profit group dedicated to promoting the practice and philosophy of Open Source software development and Open Science within the biological research community.

Open Source software has flourished in the bioinformatics community for well over a decade. When the first BOSC was held in 2000, there were already many popular open source bioinformatics packages, and the number and range of these projects has increased dramatically since then. BOSC covers the wide range of open source bioinformatics software being developed, and encompasses the growing movement of Open Science, with its focus on transparency, reproducibility, and data provenance. We welcome submissions relating to all aspects of bioinformatics and open science software, including new computational methods, reusable software components, visualization, interoperability, and other approaches that help to advance research in the biomolecular sciences. Two full days of talks, posters, panel discussions, and informal discussion groups will enable BOSC attendees to interact with other developers and share ideas and code, as well as learning about some of the latest developments in the field of open source bioinformatics.

Key dates:

  • March 3, 2015 - Call for abstracts opens
  • April 3, 2015 - Abstract submission deadline
  • May 9, 2015 - Authors notified
  • July 10-11, 2015 - BOSC 2015
  • July 10-14, 2015 - ISMB/ECCB 2015

Keynote Speakers

  Holly Bik, University of Birmingham

  Ewan Birney, EMBL-EBI

Co-Chairs:
  Peter Cock <This email address is being protected from spambots. You need JavaScript enabled to view it.> (James Hutton Institute, Scotland, UK)
  Nomi L. Harris <This email address is being protected from spambots. You need JavaScript enabled to view it.> (Lawrence Berkeley National Laboratory, USA)

Organizing Committee members:
  Monica Munoz-Torres (Berkeley Bioinformatics Open Source Projects)
  Brad Chapman (Harvard School of Public Health, USA)
  Robert Davey (The Genome Analysis Centre, UK)
  Christopher Fields (National Center for Supercomputing Applications, USA)
  Karsten Hokamp (Smurfit Institute of Genetics, Trinity College Dublin, Ireland)
  Hilmar Lapp (Duke University, USA)

 

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HitSEQ: High Throughput Sequencing Algorithms & Applications

URL: http://hitseq.org

Date: Friday, July 10 & Saturday, July 11

Start Time: 8:30 a.m - 6:00 p.m.

Room: Liffey Hall 2

The Conference on High Throughput Sequencing Methods and Applications (HiTSeq 2015) is a Satellite of the ISMB 2015 conference and brings together biologists and computational scientists interested in exploring the challenges and opportunities in the analysis of high-throughput sequencing (HTS) technologies. HiTSeq 2015 is devoted to the latest advances in computational techniques for the analysis of high-throughput sequencing data including novel algorithms, analysis methods and applications in biology where high-throughput sequencing data has been transformative. It provides a forum for in-depth presentations of novel algorithms, analysis methods, and applications in multiple areas of biology that HTS is transforming. This year we are hosting two special emphasis sessions on “Big Data In Genomics” and “Clinical genomics”. We are soliciting high-quality full papers that will undergo rigorous peer-review. Especial consideration will be given to works on the emphasis areas of this year, but other topics as described below are welcome as well. If accepted, these contributions will be presented at the conference and published in Bioinformatics online. Simultaneously, short abstract submissions will be accepted for either a brief oral presentation or presentation during the poster session.

Confirmed Keynote speakers: 

  Richard Durbin, Head of Computational Genomics at the Wellcome Trust Sanger Institute   
  Emmanouil Dermitzakis, University of Geneva


Possible Topics include:

  • Big Data in genomics (special topic)
  • Clinical genomics (special topic)
  • Detecting genome variation
  • Transcriptome analysis
  • Epigenomics and chromatin regulation (including 5-C, Hi-C etc.)
  • Cancer genomics
  • Metagenomics
  • Human microbiome
  • Analysis of 3rd and 4th generation sequencing platform data

Key Dates/Deadlines:

  • Full paper deadline: April 7
  • Abstract deadline: May 12
  • Author notifications: May 26
  • Early Registration Ends: June 5
  • Meeting Program: July 10-11

Organizers:
Valentina Boeva, Ph.D. Institut Curie, Paris 75005, France
Ana Conesa, Ph.D. University of Florida, Gainesville, Florida, USA
Francisco M. De La Vega, D.Sc. Stanford University, Stanford CA, USA
Dirk J. Evers, Ph.D. Molecular Health GmbH, Heidelberg, Germany
Kjong-Van Lehmann, Ph.D. Memorial Sloan-Kettering Cancer Center, New York, NY, USA

Editorial Coordination:
Gunnar Rätsch, Ph.D. Memorial Sloan-Kettering Cancer Center, New York, NY, USA

 

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Integrative RNA Biology - SIG (IRB-SIG)

URL: http://irbgroup.org/irb-sig-15/

Date: Friday, July 10

Start Time: 8:30 a.m - 6:00 p.m.

Room: Liffey Meeting 2

The meeting for Integrative RNA Biology brings together computational and experimental experts that drive new advances in RNA biology and overcome the computational challenges involved.

The meeting covers different aspects of RNA biology, such as alternative splicing, alternative polyadenylation (APA), post-transcriptional regulation, RNA 2D/3D structure, and the expression and function of non-coding RNAs, such as micro-RNAs (miRNAs), small-interfering RNAs (siRNAs), PIWI-interacting RNAs (piRNAs), or long non-coding RNAs (lncRNA). Studying these functional RNAs in the context of disease and therapeutics using high-throughput technologies such as RNA-Seq and CLIP-Seq, raise many computational challenges that are discussed at the meeting.

This year we have an exciting line-up of researchers from academia and industry that cover advances and challenges in RNA quantification methods, targeting RNAs for therapeutic application, the role of RNA binding proteins in cancer, RNA processing, epigenetics, lncRNA and evolution.

Join us to learn more about RNA biology and the computational challenges involved. The meeting includes invited talks, short talks selected from submitted abstracts, and an interactive poster session with a poster prize. The meeting concludes with a dinner that will give you a chance to mingle and interact with organizers, speakers, and other attendees in an informal and relaxed setting.

More details about key dates, abstract submission process and invited speakers can be found at: http://irbgroup.org/irb-sig-15/
We hope to see you with us at the IRB-SIG 2015 in July 10th, Dublin, Ireland.


Confirmed Speakers:
Nicole Meisner (Novartis, Switzerland)
Mar Alba (IMIM & ICREA, Barcelona, Spain)
Cathal Seoighe (National University of Ireland)
Magnus Rattray (University of Manchester, England)
David Elliott (Newcastle University, England)


Organizers:
Yoseph Barash, University of Pennsylvania, United States This email address is being protected from spambots. You need JavaScript enabled to view it.
Eduardo Eyras , UPF & ICREA, Barcelona, Spain, This email address is being protected from spambots. You need JavaScript enabled to view it.
Klemens Hertel, UC Irvine, United States, This email address is being protected from spambots. You need JavaScript enabled to view it.

 

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NetBio SIG

URLhttp://nrnb.org/netbiosig/

Date: Friday, July 10

Start Time: 8:30 a.m - 6:00 p.m.

Room: Wicklow Hall 2B

Overview:
Biological networks provide a context for integrating and analyzing massive amounts of diverse kinds of measurement data, such as expression data from RNA-Seq, protein abundance  and interaction data from mass spectrometry, and genetic data from association studies. Network theory provides powerful analysis techniques that can be used to develop insights into large amounts of data. Our use of networks in biology has changed from purely representational and didactic purposes to more analytic and hypothesis formulation purposes. This shift has resulted, in part, from the confluence of advances in computation, informatics, and high throughput techniques in systems biology.

We will solicit abstracts that cover new developments in network biology, focusing on two major areas: (1) the development of network-related tools and resources, and (2) the application of network analysis and visualization in the study of biology, synthetic biology and medicine. The meeting will provide a unique meeting space for tool developers and users in the field of network biology. Through these complementary lenses, the meeting will bring into focus the current state of the field, its future promise and how to get there.

How to Participate:
Find the latest information including how to submit an abstract for the upcoming NetBio community meeting.  In addition to the annual meeting, the NetBio group functions year-round as an international virtual community supporting and co-organizing multiple meetings, connecting researchers, results, resources and training opportunities. Find out more via the NetBio Group at LinkedIn.

Keynote Speakers:
Ron Shamir - Do networks help in making sense of the omics data deluge? - Tel Aviv University, Israel
Henning Hermjakob - Open Community Standards in Proteomics and Systems Biology - The European Bioinformatics Institute (EBI), UK
Brenda Andrews - Global Mapping of Genetic Networks in Yeast - University of Toronto, Canada
Florian Markowetz - Functional analysis of genetic interaction networks - University of Cambridge, UK

Organizers:
Alexander Pico, Gladstone Institutes, United States, This email address is being protected from spambots. You need JavaScript enabled to view it.
Scooter Morris, University of California, San Francisco, United States, This email address is being protected from spambots. You need JavaScript enabled to view it.
Gary Bader, University of Toronto, Canada, This email address is being protected from spambots. You need JavaScript enabled to view it.
Mario Albrecht, Graz University of Technology, Austria, This email address is being protected from spambots. You need JavaScript enabled to view it.
Natasa Przulj, Imperial College London, United Kingdom, This email address is being protected from spambots. You need JavaScript enabled to view it.
Esti Yeger Lotem, National Institute for Biotechnology in the Negev, Israel, This email address is being protected from spambots. You need JavaScript enabled to view it.
Frank Kramer, University Medical Center Göttingen, Germany, This email address is being protected from spambots. You need JavaScript enabled to view it.
Martina Kutmon, University of Maastricht, The Netherlands, This email address is being protected from spambots. You need JavaScript enabled to view it.

 

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Regulatory Genomics Special Interest Group (RegGenSIG)

URL:http://light.ece.ohio.edu/~reggen/2015/

Date: Saturday, July 11

Start Time: 8:30 a.m - 6:00 p.m.

Room: Wicklow Hall 2B

Regulatory genomics involves the study of the genomic ‘control system,’ which determines how, when and where to activate the ‘blueprint’ encoded in the genome. Regulatory genomics is the topic of much research activity worldwide. Since computational methods are important in the study of gene regulation, the RegGenSIG meeting focuses on bioinformatics for regulatory genomics. An important goal of the meeting is to foster a collaborative community wherein scientists convene to solve difficult research problems in all areas of computational regulatory genomics.

RegGenSIG is an activity of the ISCB Special Interest Group for Regulatory Systems Genomics, (http://www.iscb.org/iscb-sigs-regsys), a community of shared interest that has multiple activities and interactions throughout the year, rather than solely meeting during the ISMB conference. An important goal of the SIG is to foster a topically-focused collaborative community wherein scientists communicate with one another on research problems and/or opportunities in the area of computational biology as it pertains to regulatory and systems genomics.


CALL FOR ABSTRACTS:

To make an oral presentation at RegGenSIG, extended abstracts (2-3 pages) should be submitted by April 27, 2015. Based on the submitted abstracts, each author will be invited to make either an oral presentation or a poster presentation. Authors will be notified by May 8, 2015. For poster presentations, authors should submit a 250 word abstract no later than May 18, 2015. Author notification will occur no later than May 25, 2015.

RegGenSIG 2015 - Extended abstractTo make an oral presentation at RegGenSIG, extended abstracts (2-3pages) should be submitted by April 27, 2015, to Finn Drablos (This email address is being protected from spambots. You need JavaScript enabled to view it.).

ABSTRACT SUBMISSION INSTRUCTIONS:

Extended abstract:
To make an oral presentation at RegGenSIG, extended abstracts (2-3 pages) should be submitted by April 27, 2015, to:
Finn Drablos (This email address is being protected from spambots. You need JavaScript enabled to view it.), with Subject "RegGenSIG 2015 - Extended abstract".

Poster abstract:
To make a poster presentation at RegGenSIG, poster abstracts (250 words) should be submitted by May 18, 2015, to:
Finn Drablos (This email address is being protected from spambots. You need JavaScript enabled to view it.), with Subject "RegGenSIG 2015 - Poster abstract".
 
KEY DATES:

  • April 27, 2015  Due date for extended abstracts (2-3 pages) for oral presentations
  • May 8, 2015     Author notification for oral presentations
  • May 18, 2015   Due date for short abstracts (250 words) for poster presentations
  • May 25, 2015   Author notification for poster presentations
  • June 6, 2015   Early registration cut-off date
  • July 11, 2015   RegGenSIG meeting



RegGen SIG Organizers      
Finn Drablos, Norwegian University of Science and Technology Trondheim, Norway, This email address is being protected from spambots. You need JavaScript enabled to view it.
Lonnie Welch, Ohio University Athens, United States, This email address is being protected from spambots. You need JavaScript enabled to view it.
Saurabh Sinha, University of Illinois Urbana, United States This email address is being protected from spambots. You need JavaScript enabled to view it.
Stein Arts, University of Leuven, Belgium This email address is being protected from spambots. You need JavaScript enabled to view it.
Morgane Thomas-Chollier, Institut de Biologie de l'ENS (IBENS), Paris, France
Jason Ernst, University of California, Los Angeles, United States, This email address is being protected from spambots. You need JavaScript enabled to view it.

 

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VarI SIG

URL: http://varisig.biofold.org

Date: Saturday, July 11

Start Date: Saturday July 11, 8:30 a.m - 6:00 p.m.

Sunday July 12,  10:30 AM - 12:25 PM,

Room: Liffey Meeting 2

The primary goal of the VarI-SIG is to outline and discuss the recent advances in the methodology for the annotation and analysis of genomic variation data.

Genetic variants are generally interesting in the context of their phenotypic manifestations. The discrepancy between the availability of SNV data and the current lack of its interpretation requires the development of methods for the annotation/prediction of the genetic variant impact. In the near future the analysis of genetic variation will be a key factor for the understanding of the information encoded in the genome.

The VarI-SIG provides a forum for the organization of a research network, a community of scientific interest (COSI), facilitating the exchange of ideas and the establishment of new collaborations bringing together varying expertise. It thus supports the unprecedented collaborative effort to manage the complexity of the analysis and evaluation of genetic variation.

The meeting will be divided into two sessions - "SNVs as markers: evolution, populations, GWAS" and "Genetic variants as effectors: function, structure, and regulation". This year, in the context of the newly introduced ISMB/ECCB Disease Thematic Area, we will also follow our regular meeting day with a half-day session within the main conference. We have an exciting program planned for the event including keynote talks, invited presentations, a roundtable discussion and a poster session. For detailed information please see the SIG website.

We are interested in submissions describing original work in all the fields of genomic variation research including, but not limited to:

  • Databases, data mining algorithms and visualization tools for genetic variants analysis.
  • Methods for predicting regulatory/structural/functional impacts of SNVs
  • Personal Genomics, GWAS studies and SNV prioritization
  • Population genomics and phylogenetic analysis


ABSTRACT SUBMISSION
VarI-SIG accepts submissions for presentation proposals (2-3 pages) and poster abstracts.
Both contributions should be submitted by April 12, 2015.
Acceptance notification will be sent out by April 26, 2015.

Please indicate in your submission of presentation proposals if you DO NOT plan to attend the main conference and DO NOT wish to present on the second day of the SIG
Abstract should be submitted through EasyChair using the following URL
https://www.easychair.org/conferences/?conf=varisig2015

KEY DATES

  • April 12, 2015 - Poster Abstract and Presentation Proposal submissions deadline
  • April 26, 2015 - Poster and Presentation Proposal acceptance notifications.
  • May 10, 2015 - Preliminary SIG Program Available
  • May 29, 2015 - Complete SIG Program Available
  • June 6, 2015 - Early registration cut-off date
  • July 11, 2015 - Vari-SIG meeting


SIG CHAIRS
Yana Bromberg, Rutgers University, USA
Emidio Capriotti, University of Alabama, USA
Hannah Carter, University California, San Diego, USA

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Highlights Area Chairs Information

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Expectations of editors for Highlights Track
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Expectations of editors for Highlights Track
- Pro-actively recruit the submission of the best presentations you have heard over the last year (this is a very important component of your task!).
- Reserve some of your time for this job between March 3 and March 26, 2014.
- Rank and decide on accept/reject a list of 15-25 published papers submitted for presentation.
- Write short summary for each paper motivating your decision.
- Important: participate in final selection made through telephone conference on Wednesday, Mar 26 (11-12:30 EST).
- Chair a session at ISMB 2014 (at least 60% of the editors will be needed there!).


--------------------------------------------------
More details
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On October 14, we will invite the submission of full papers that have been published between 2013 and the submission deadline (February 28, 2014) or are in press at that point. A group of experts will select the papers to be presented at the meeting considering the impact of the work on the field, the likelihood that the work makes a good presentation, and the relevance for molecular and medical biology, in general.

Submissions must include a 250-word abstract-like argument that explains how the submitted paper(s) suit the goal of presenting highlights that impacted the field. The person who will present will be identified upon submission. Submitters can add links to videos downloaded to Google Video/YouTube/SciVee that demonstrate their presentation skills if they may wish to do so. This should enable editors to handpick the work most relevant, interesting, and of highest value for as many attendees as possible. The impact of the publication should be a criterion as well as the 'presentability' in a talk to a large audience, and the skills of the dedicated presenter.

These 'soft' criteria attempt to capture the underlying concept, namely the presentation of exciting and thought-provoking seminars that will both contribute to the success and attraction-value of ISMB and to the impact the meeting has on advancing computational biology and bioinformatics. The criterion of presentability accounts for the fact that some papers that will completely change the field, or will become citation records may not translate to exciting seminars.

All submissions will be evaluated by a group of editors with formidable expertise in their respective fields, and we hope that you will accept the invitation to become one of these. Upon submission, the authors will identify the editor/expert most suitable to review their work according to either their knowledge of the work of this expert or keywords provided by you.

The PDFs of all published (in press) papers with the covering 250-word argument that explains how the papers suit the selection criteria will have to be submitted through the automated system by February 28, 2014 (midnight by any time zone). No reason will exempt submissions from this deadline.

The chairs will notify authors of the acceptance by April 4, 2014.

Only one submission will be accepted per presenter, and maximally 5 per co-author/group leader on any of the submissions. Although we feel that your efforts should not be punished by not letting you submit, we hope that you will somehow restrict the number of papers submitted with you as a co-author/group leader.

The selected Highlights will be presented in tracks that run in parallel to the main meeting and merged with accepted Proceedings in subject-oriented sessions. All presentations will have to be completed within 20 minutes and will be followed by 5-minute discussions. While presenters are expected to focus mostly on the chosen paper(s), short infusions of more recent data are highly encouraged.

All editors will have rank the submissions, suggest accept/reject, and write a short summary motivating their decision. It remains to be discussed whether or not those evaluations will be communicated to the submitters.

Depending on the quality of the submissions, about 35-42 presentations will be accepted.

The details about how the Editors will review their assignments will be left to them. They may want to add colleagues as helpers to dissipate their load and they may invite input from external reviewers. In any case, we encourage editors to seek some input from their groups/peers. However, ultimately we invite you because of your expertise in accomplishing this assignment adequately. We have no doubt that you will find the best possible solution without directions/rules from us.

Please contact Steven Leard (This email address is being protected from spambots. You need JavaScript enabled to view it.), Reinhard Schneider, and Burkhard Rost with further questions.

Reinhard Schneider & Burkhard Rost, Highlights Co-chairs

Registration

 

Registration for ISMB/ECCB 2015 will open Wednesday, March 25!   We look forward to your participation in Dublin!   As a reminder, if you require a visa please register early as receiving a visa can take 8-12 weeks.

News

ISMB ECCB 2015 - A Welcome from Des Higgins


Special Issue of Bioinformatics

The special issue of Bioinformatics which serves as the proceedings of the joint 23rd annual meeting of Intelligent Systems for Molecular Biology (ISMB) and 14th European Conference on Computational Biology (ECCB) in now available here.

 

 

Conference Reception at the Guinness Storehouse Added to Social Events

Monday, July 13                7:30 pm – 10:30 pm
Location: Guinness Storehouse
St. James’s Gate, Dublin 8, Ireland
Click To download a Map 

*Cost: €25.00   Includes entrance, light reception style dinner and one complimentary pint of world famous Guinness (or wine or soft drink).

Event details here.

Please note transportation is not provided to attend this event. The walk time from the Convention Centre Dublin is approximately 30-35 minutes. Other options include public transit or taxi.

 


 Award Winners

ISCB/ECCB 2015 Award Winners Announce: Cyrus Chothia, Curtis Huttenhower and Larry Hunter

 


Meet in Dublin

Additional ISMB/ECCB 2015 promotional materials available here

 


 

 

 

 

Exclusively for members

  • Member Discount

    ISCB Members enjoy discounts on conference registration (up to $150), journal subscriptions, book (25% off), and job center postings (free).

  • Why Belong

    Connecting, Collaborating, Training, the Lifeblood of Science. ISCB, the professional society for computational biology!

     

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