ISMB 2008 ISCB

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 



Agenda

Click on the presentation iconto access the PDF slides of each talk.
[ Friday, Dec 5 ] [ Saturday, Dec 6 ] [ Sunday, Dec 7 ]
Thursday – December 4, 2008
3:00 pm – 6:00 pm Registration
Friday - December 5, 2008
7:30 am – 9:30 am Registration & Continental Breakfast
8:30 am – 9:15 am Keynote 1
Cellular Network Based Identification of Master Regulators of Physiological and Oncogenic Processes
Andrea Califano, Ph.D., Columbia University
9:15 am – 10:25 am Oral Presentations 1 - 7
  Oral Presentation 1
A Comparison of Next-state (dynamic) and Co-temporal (static) Modeling of Time Course Data: Multiple Approaches Provide Complementary Information
Presenter: Edward E. Allen, Wake Forest University
Additional Author(s): David J. John,
William H. Turkett, Stan J. Thomas, Richard F. Loeser,
Leslie B. Poole, Elizabeth M. Hiltbold,
Jacquelyn S. Fetrow
Oral Presentation 2
Evaluating Relevance Ranking and Query Expansion for MEDLINE Retrieval
Presenter: Zhiyong Lu, NCBI
Additional Author(s): Kim Won, John Wilbur
Oral Presentation 3
On the Cache-Awareness in DNA Probe Selection
Presenter: Carl Bergenhem,
University of Connecticut
Additional Author(s): Chih Lee and Chun-Hsi Huang
Oral Presentation 4
Laboratree: Extensible Basic Research Application and Data Management Using the OpenSocial Platform
Presenter: Jamison R. Hemmert, Indiana University
Additional Author(s): Brandon Peters, Joshua D. Waymire, Kishore K. Kamati, Peter H. Baenziger,
Craig A. Sanders, Joy A. Nellis, Justin J. Dantzer,
Peter J. Serguta, Jessica L. Dantzer,
Sean D. Mooney
Oral Presentation 5
Beyond Dictionary Match for Disease Named Entity Recognition
Presenter: Robert Leaman, Arizona State University
Additional Author(s): Christopher Miller,
Graciela Gonzalez
Oral Presentation 6
Graph Theoretic Properties of Known Complexes
Presenter: Suzanne Gallagher, University of Colorado
Additional Author(s): Debra S. Goldberg
Oral Presentation 7
Discovery of HuR Binding Sites Using a Machine Learning Approach
Presenter: Shweta Bhandare,
University of Colorado Boulder
Additional Author(s): Debra Goldberg, Jon Miller,
Paul Johnson, Nick Farina
10:25 am – 10:45 am AM Break
10:45 am – 11:45 am Oral Presentations 8 - 13
  Oral Presentation 8
Textual Characteristics of Full-text Biomedical Journal publications in Open Access vs. Traditional Journals
Presenter: Karin Verspoor,
University of Colorado Denver
Additional Author(s): K. Bretonnel Cohen,
Larry Hunter
  Oral Presentation 9
A Collaborative Framework for Knowledge Guided Exploration
Presenter: Scott Fujan, University of Tulsa
Additional Author(s): Cody Pollet, Stephen Tyree, John Hale
  Oral Presentation 10
JANUS - A System for Annotating, Vetting and Testing Natural Language Processing Systems
Presenter: Anni Coden,
IBM T.J. Watson Research Center
Additional Author(s): Michael Tanenblatt,
Anni Coden, Igor Sominsky
  Oral Presentation 11
Using Protein Functional Features to Predict Deleterious Mutations Using Saturation Mutagenesis Data
Presenter: Uday S. Evani, Indiana University
Additional Author(s): Uday S. Evani, Vidhya Krishnan, Sean D. Mooney
  Oral Presentation 12
An Abstraction for Quantitatively Capturing Stochastic Bistable Oscillations in Enzymatic Futile Cycle
Presenter: Hiroyuki Kuwahara,
The Microsoft Research - University of Trento
  Oral Presentation 13
Learning Causal Relationships between Genes from Steady State Data: Algorithms, Simulation and Application
Presenter: Michael P. Verdicchio,
Arizona State University
Additional Author(s): Xin Zhang, Seungchan Kim, Chitta Baral
11:45 pm – 12:30 pm Keynote 2
Next-generation Extraction: Ad-hoc Knowledge Networks
Graciela Gonzalez, Arizona State University
12:30 pm – 4:00 pm Break
4:00 pm – 5:00 pm Workshop Session:
Computational Bioethics: Issues and Didactic Strategies
Presenters:
Lawrence Hunter
Director, Computational Bioscience Program, UC Denver

Mark Yarborough, Director
Center for Bioethics and the Humanities, UC Denver
5:00 pm – 6:00 pm Oral Presentations 14 - 19
  Oral Presentation 14
Reflect – Augmented Browsing for the Life Scientist
Presenter: Reinhard Schneider, EMBL Heidelberg
Additional Author(s): Evangelos Pafilis, Seán I. O’Donoghue, Lars J. Jensen, Heiko Horn, Michael Kuhn, Nigel P. Brown
Oral Presentation 15
Using the OpenSocial Platform to Develop Open, Exchangeable Web Based Biomedical Research Applications
Presenter: Joshua Waymire, Indiana University
Additional Author(s): Brandon Peters,
Jessica L. Dantzer, Sean D. Mooney
Oral Presentation 16
Category Theory and the Notion of Natural in Bioinformatic Models
Presenter: Peter Salamon, San Diego State University
Additional Author(s): James Nulton, David Aaby, Andrew Detzel, Barbara Bailey
Oral Presentation 17
A Novel Gene Regulatory Model for Embryonic Cell Differentiation in Drosophila Melanogaster
Presenter: Tejaswi Gowda, Arizona State University
Additional Author(s): Sarma Vrudhula,
Seungchan Kim
Oral Presentation 18
Was Vioxx the Culprit?
Presenter: Jack Horner, Independent Researcher
Oral Presentation 19
Optimizing Proteomic Biomarker Discovery – Incorporating Prior Experimental Data
Presenter: David Gnabasik,
University of Colorado Boulder
Additional Author(s): Mark Duncan, David Gnabasik
6:30 pm – 10:00 pm Banquet
Location: Il Poggio Restaurant, Snowmass Village
[TOP] [ Friday, Dec 5 ] [ Saturday, Dec 6 ] [ Sunday, Dec 7 ]
Saturday, December 6, 2008
7:30 am – 9:30 am Registration & Continental Breakfast
8:30 am – 9:15 am Keynote 3
Biomedical Informatics: Its Scientific Evolution and Future Promise
Edward H. Shortliffe, MD, PhD, University of Arizona, Phoenix
9:15 am – 10:25 am Oral Presentations 20 - 26
  Oral Presentation 20
Mechanism-based Inference of Drugs to Diseases using Drug-driven Ontologies and Semantic Infrastructure

Presenter: Eric Neumann, Science Commons, MIT
Additional Author(s): Angela Qu, Ranga Gudivada, Bruce Aronow
Oral Presentation 21
Sequence Cooccurrence and Covariation Suggest Specific Physical Interactions Between Type VI Secretion System Components
Presenter: J. Gregory Caporaso,
University of Colorado Denver
Additional Author(s): Amy Dear, Larry Hunter, Marcelo Sousa, Rob Knight
Oral Presentation 22
Modelling Elastin Self-Assembly
Presenter: Hongyan Song, Hospital for Sick Children
Additional Author(s): John Parkinson
Oral Presentation 23
A Statistical Framework for Differential Network Analysis (DNA) from Microarray Data using Partial Least Squares
Presenter: Susmita Datta, University of Louisville
Additional Author(s): Ryan Gill, Vasyl Pihur,
Somnath Datta
Oral Presentation 24
A Statistical Approach to Better Assess Environmental Community Taxonomy and Average Genome Size
Presenter: Florent Angly, San Diego State University
Additional Author(s): Dana Willner, Robert Schmieder, Forest Rohwer
Oral Presentation 25
Sponge Evolution and the Rise of Animals
Presenter: Davide Pisani, The National University of Ireland Maynooth
Additional Author(s): Erik Sperling, Kevin J. Peterson
Oral Presentation 26
Archaebacterial Homologs are More Central to Eukaryotic Metabolism than Eubacterial Homologs
Presenter: James McInerney,
National University of Ireland
Additional Author(s): James Cotton
10:25 am – 10:45 am AM Break
10:45 am – 11:45 am Oral Presentations 27 - 32
  Oral Presentation 27
Atomic Density Sheds Light on the Evolutionary Characteristics of Proteins
Presenter: Jennifer Commins, Smurfit Inst of Genetics, Trinity College Dublin
Additional Author(s): Jennifer Commins
and Mario Fares
Oral Presentation 28
Reverse-engineering Protein Interaction Network Evolution
Presenter: Todd A. Gibson,
University of Colorado Denver
Additional Author(s): Debra S. Goldberg
Oral Presentation 29
The Phylogeny of the MHPs and Beyond
Presenter: Mary J. O'Connell, Dublin City University
Additional Author(s): Noeleen B. Loughran,
Brendan O'Connor, Ciaran O'Fagain
Oral Presentation 30
Next Generation Evolutionary Genomics: Why wait for Complete Genomes?
Presenter: Todd Castoe,
University of Colorado School of Medicine
Additional Author(s): Wanjun Gu, Jason de Koning, Vijetha Vemulapalli, David Pollock
Oral Presentation 31
Rapid Inference of Complex Patterns of Protein Evolution from Large Phylogenomic Data Sets
Presenter: Jason de Koning,
University of Colorado Denver
Additional Author(s): Wanjun Gu, David D. Pollock
Oral Presentation 32
Looking for a Needle in a Haystack - Identifying Transcription Factor Binding Sites Using a Phylogenetic Magnifying Glass
Presenter: Elizabeth Siewert,
University of Colorado Denver
Additional Author(s): Katerina Kechris
11:45 am – 12:30 pm Keynote 4
New Computational Tools for Investigating the Systems Biology of Heart Development
Vincent VanBuren, Texas A & M HSC College of Medicine
12:30 pm – 4:00 pm Break
4:00 pm – 5:30 pm Oral Presentations 33 - 41
  Oral Presentation 33
Gene Function Prediction Using Prior Knowledge and Expression Data
Presenter: Luis Tari, Arizona State University
Additional Author(s): Chitta Baral, Seungchan Kim
Oral Presentation 34
Natbox: A Network Analysis Toolbox in R
Presenter: Shweta S. Chavan,
UALR / UAMS Joint Bioinformatics program
Additional Author(s): Marco Scutari,
Radhakrishnan Nagarajan
Oral Presentation 35
Towards a Multi-Level Calculus for Cellular Modeling and Simulation
Presenter: Rayus Kuplicki, University of Tulsa
Additional Author(s): Stephen Tyree,
Trevor Sarratt, Scott Fujan, John Hale
Oral Presentation 36
Improving the Prediction of Regulatory SNPs Using Functional Information
Presenter: Yiqiang Zhao, Indiana University
Additional Author(s): Matt Mort, David Cooper,
Sean Mooney
Oral Presentation 37
A Two-stage Adaptive Design can Increase Power for Multiple Comparisons
Presenter: Deborah Glueck,
Colorado School of Public Health
Additional Author(s): Anis Karimpour-Fard
Oral Presentation 38
A New Mapping Tool for Next Generation Sequencing Reads
Presenter: Alex Poole, University of Colorado
Additional Author(s): Wanjun Gu, and David Pollock
Oral Presentation 39
Predicting Temperature-sensitive Mutations Derived From Single Amino Acid Substitutions
Presenter: Ping Ye, Washington State University
Oral Presentation 40
Entity Mention Normalization - Taking Another Step Towards Integrating Data Extracted from Literature with Databases
Presenter: Jörg Hakenberg, Arizona State University
Additional Author(s): Graciela Gonzalez
Oral Presentation 41
Extended Analysis and Prediction of Gain and Loss of Phosphorylation Sites in Cancer
Presenter: Peter H. Baenziger,
Indiana University School of Medicine
Additional Author(s): Maricel G. Kann, Matthew Hahn, Matthew E. Mort, Predrag Radivojac,
Sean D. Mooney
5:30 pm – 7:30 pm Poster Session/Reception
Location: Eldorado A&B Room, Silvertree Hotel
[TOP] [ Friday, Dec 5 ] [ Saturday, Dec 6 ] [ Sunday, Dec 7 ]
Sunday, December 7, 2008
7:30 am - 9:30 am Registration & Continental Breakfast
8:30 am – 9:15 am Keynote 5
Visual Analytics and Flow Cytometry Visualization using SFA
Chris Shaw, Simon Fraser University
9:15 am – 10:15 am Oral Presentations 42 - 48
    Oral Presentation 42
MutDB: Enhanced Biochemical Analysis of Structural and Functional Features of Genetic Variations
Presenter: Kishore Kamati, Indiana University
Additional Author(s): Rakesh Sathyesh, Matthew Mort, Arti Singh, Adebayo Olowoyeye, Jessica Dantzer, Charles Moad, Vidhya G. Krishnan, Peter H. Baenziger, Maricel G. Kann, Predrag Radivojac, Randy Heiland, Sean D. Mooney
Oral Presentation 43
Molecular Characterization of Insertional Mutagenesis Sites in Gene Therapy Studies
Presenter: Jessica Dantzer, Indiana University School of Medicine Center
Additional Author(s): Brandon Peters, Sara Dirscherl, Jonathan Nowacki, Scott Cross, Xiaoman Li, Kenneth Cornetta, Mary C. Dinauer, Sean D. Mooney
Oral Presentation 44
Steps Toward Broad-spectrum Countermeasures: Discovering Virulence-associated Genes Present in Diverse Pathogens
Presenter: Chris Stubben, Los Alamos National Lab
Additional Author(s): Melanie Duffield,
Murray Wolinsky
Oral Presentation 45
Modeling the Malaria Parasite-Mosquito Midgut Cell Interactions
Presenter: Ezekiel Adebiyi, Covenant University
Additional Author(s): Gbenga Oluwagbemi,
Seydou Doumbia
Oral Presentation 46
Use of NMPDR Subsystems-based Annotation and Genome Comparison Tools for Understanding Streptococcus Pyogenes Virulome
Presenter: Ramy Aziz, San Diego State University and Cairo University
Additional Author(s): Leslie K. Mcneil, Ross Overbeek, Rick Stevens, Veronika Vonstein, Malak Kotb,
Robert A. Edwards
Oral Presentation 47
Sensitive and Specific Cross-Species cDNA-to-Genome Alignment with Spaced Seeds
Presenter: Leming Zhou, University of Pittsburgh
Additional Author(s): Liliana Florea
Oral Presentation 48
Prediction of Functional Sites in Predicted Protein Structures Using Dynamics Perturbation Analysis
Presenter: Judith D. Cohn,
Los Alamos National Laboratory
Additional Author(s): Michael E. Wall
10:35 am - 10:45 am AM Break
10:45 am – 11:45 am Oral Presentations 49 - 55
  Oral Presentation 49
Reconstructing the Metabolic Network: a Probabilistic Approach to Improve Enzyme Prediction
Presenter: Stacy Hung, Hospital for Sick Children
Additional Author(s): James Wasmuth,
John Parkinson
Oral Presentation 50
The Topology of the Bacterial Co-conserved Protein Network and its Implications for Predicting Protein Function
Presenter: Anis Karimpour-Fard,
University of Colorado Denver
Additional Author(s): Sonia M. Leach, Ryan T. Gill, Lawrence E. Hunter
Oral Presentation 51
High Throughput Metagenome Analysis
Presenter: Rob Edwards, San Diego State University
Oral Presentation 52
Computational Assessment of Screening Statistics with NoiseMaker
Presenter: Phoenix Kwan, ThermoFisher Scientific
Additional Author(s): Amanda Birmingham
Oral Presentation 53
COBRA: A Web-based Tool for Genotype/phenotype Data Management
Presenter: Brandon Peters, IU School of Medicine
Additional Author(s): Rebecca Fletcher, Kirthi Krishnamraju, Anne Nguyen, Jason Robarge, Lang Li, Mark Crowder, Todd Skaar, David Flockhart,
Sean Mooney
Oral Presentation 54
Analysis of Workflows on Inexpensive, Massive Computational Grids in the Cloud
Presenter: Jason A. Stowe, Cycle Computing
Additional Author(s): Ian D. Alderman,
Dr. Irene M. Ong
Oral Presentation 55
Analyses of Features for Prediction of Protein-protein Interactions in Protein Hetero-complexes and Their Impact on Human Disease
Presenter: Angshuman Bagchi, Indiana University School of Medicine
Additional Author(s): Eunseog Youn, Sean D. Mooney
11:45 am – 12:30 pm Keynote 6
Hybrid Computers Need Hybrid Algorithms
Kirk E. Jordan, Computational Science Center,
IBM T.J. Watson Research Center
12:30 pm Adjourn


[TOP] [ Friday, Dec 5 ] [ Saturday, Dec 6 ] [ Sunday, Dec 7 ]