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             ISCB Statement 
              on Bioinformatics Software Availability 
            I. Introduction 
              Conditions of bioinformatics software availability are extremely 
              important to the field of bioinformatics. The ISCB, a professional 
              society of 1300 bioinformatics scientists, has discerned significant 
              confusion in recent months regarding the topic of software availability, 
              and is disseminating this statement to clarify several issues regarding 
              software availability, and to make recommendations on software availability 
              policies for government agencies that fund bioinformatics research. 
            II. Recommendations 
            
              - The term 
                open source has taken on many different meanings. 
                This term creates confusion in discussions of software availability; 
                therefore the term should be carefully qualified to indicate which 
                variation of the open-source model is intended.
 
              - Government 
                agencies that fund bioinformatics research should NOT REQUIRE 
                that software produced with government research funds must be 
                distributed under open-source license (particularly given the 
                ambiguity in the meaning of that term). Because of the complexity 
                inherent in software, no single distribution model is appropriate 
                for all research projects. Government agencies should require 
                clear statements of software availability in grant proposals.
 
              -  As reviewers 
                of bioinformatics grant applications, ISCB scientists have noted 
                that these applications often contain confusing or unclear statements 
                regarding the availability of software that will be developed 
                under government grant funds. This statement contains several 
                definitions of software availability that ISCB recommends for 
                use in bioinformatics grant applications. ISCB recommends one 
                of those definitions as a minimal requirement of software availability 
                that funding agencies should require.
 
             
            III. ISCB 
              Levels of Software Availability 
              The International Society for Computational Biology (ISCB) provides 
              the following definitions of software availability. It is ISCBs 
              intent that these definitions be a standard reference. It is recommended 
              that all software availability be defined in these terms (or specific 
              stated variations thereof) and stated in all publications, grant 
              applications, and other documents that describe software availability. 
            ISCB recommends 
              that government funding agencies that support bioinformatics research, 
              require a minimum of ISCB Level 0 Availability. 
            The levels of 
              availability listed here are not meant to be exhaustive. Researchers 
              may want to define variations to these levels, but ISCB strongly 
              suggests that at least Level 0f Availability be maintained. 
            For all levels 
              of availability, the licensee must clearly acknowledge the contributions 
              of the author(s) of the original software in all redistributions. 
            ISCB Level 
              0 Availability: 
             
              a. For Research 
                Use: The software will be available free of charge, in binary 
                form, on an as is basis for research purposes to educational 
                institutions, non-profit research institutes, government research 
                laboratories, and individuals, for non-exclusive use, without 
                the right of the licensee to further redistribute the software. 
              b. For Commercial 
                Use: The software will be available in binary form, on an as 
                is basis to commercial institutions, possibly for a fee, 
                for non-exclusive use, without the right of the licensee to redistribute 
                the software. 
             
            ISCB Level 
              1 Availability (No fee): 
              The 
              software will be available free of charge to all institutions, in 
              binary form, on an as is basis, for non-exclusive use, 
              without the right of the licensee to further redistribute the software. 
            ISCB Level 
              2 Availability (No fee, source code for research use): 
              Same 
              as ISCB Level 1; in addition, source code is available for research 
              use to educational institutions, non-profit research institutes, 
              government research laboratories, and individuals, without the right 
              to redistribute the source code. 
            ISCB Level 
              3 Availability (No fee, source code to all):  
              Same as ISCB Level 1; in addition, source code is available to commercial 
              institutions. 
            ISCB Level 
              4 Availability (No fee, unlimited redistribution, with source 
              code):  
              The software will be available free of charge to all institutions 
              and individuals, in binary and source-code forms, on an as 
              is basis, for non-exclusive use. The licensee may redistribute 
              and/or resell the original software including the source code, and 
              may redistribute and/or resell any modifications or derivative works 
              created by the licensee. The licensee must clearly acknowledge the 
              contributions of the author(s) of the original software in all redistributions. 
            To contribute 
              to ISCB's open forum on ISCB's 
               Statement on 
              Bioinformatcis Software Availability, 
              (do as follows) 
            
            The statements 
              contained in this site do not constitute, and should not be construed 
              as, giving legal advice. Nothing in this site is intended to constitute 
              the giving of legal advice. The reader should consult with counsel 
              before pursuing a course of action in reliance on information contained 
              in this site. 
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